[HTML][HTML] Circular RNAs as novel regulators of β-cell functions in normal and disease conditions

L Stoll, J Sobel, A Rodriguez-Trejo, C Guay, K Lee… - Molecular …, 2018 - Elsevier
Objective There is strong evidence for an involvement of different classes of non-coding
RNAs, including microRNAs and long non-coding RNAs, in the regulation of β-cell activities …

[HTML][HTML] Circular RNA circFBXW4 suppresses hepatic fibrosis via targeting the miR-18b-3p/FBXW7 axis

X Chen, HD Li, FT Bu, XF Li, Y Chen, S Zhu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: Circular RNAs (circRNAs) are a new form of noncoding RNAs that play
crucial roles in various pathological processes. However, the expression profile and function …

Circular RNA and diabetes: epigenetic regulator with diagnostic role

K Abbaszadeh-Goudarzi, S Radbakhsh… - Current molecular …, 2020 - ingentaconnect.com
Circular RNAs, a group of endogenous non-coding RNAs, are characterized by covalently
closed cyclic structures with no poly-adenylated tails. It has been recently recommended that …

circ_0037128/miR-17-3p/AKT3 axis promotes the development of diabetic nephropathy

Q Wang, Z Cang, L Shen, W Peng, L Xi, X Jiang, X Ge… - Gene, 2021 - Elsevier
Circular RNAs (circRNAs) play vital roles in the development of diabetic nephropathy (DN).
In this study, we investigated the function of circ_0037128 and molecular mechanism via …

Expression profile of circular RNAs in placentas of women with gestational diabetes mellitus

H Wang, G She, W Zhou, K Liu, J Miao, B Yu - Endocrine journal, 2019 - jstage.jst.go.jp
Forty-five pregnant women who underwent cesarean section, including 30 cases of
gestational diabetes mellitus (GDM) and 15 normal pregnant women, were enrolled in this …

RNA-seq reveals the circular RNA and miRNA expression profile of peripheral blood mononuclear cells in patients with rheumatoid arthritis

J Wen, J Liu, P Zhang, H Jiang, L Xin, L Wan… - Bioscience …, 2020 - portlandpress.com
Abstract Objective: Circular RNAs (circRNAs) are a significant class of molecules involved in
a wide range of diverse biological functions that are abnormally expressed in many types of …

Hsa_circ_0054633 in peripheral blood can be used as a diagnostic biomarker of pre-diabetes and type 2 diabetes mellitus

Z Zhao, X Li, D Jian, P Hao, L Rao, M Li - Acta diabetologica, 2017 - Springer
Aims The purpose of the current study was to investigate the characteristic expression of
circular RNAs (circRNAs) in the peripheral blood of type 2 diabetes mellitus (T2DM) patients …

Profiling and bioinformatics analyses reveal differential circular RNA expression in hypertensive patients

N Wu, L Jin, J Cai - Clinical and Experimental Hypertension, 2017 - Taylor & Francis
Objectives: CircRNAs, a novel class of noncoding RNAs, have been reported in many
diseases. However, their role in hypertension remains unclear. Here, we aimed to determine …

Circular RNA and its mechanisms in disease: from the bench to the clinic

B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …

[HTML][HTML] CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinson's disease

Q Cheng, J Wang, M Li, J Fang, H Ding, J Meng… - Redox biology, 2022 - Elsevier
As a novel type of non-coding RNAs, covalently closed circular RNAs (circRNAs) are
ubiquitously expressed in eukaryotes. Emerging studies have indicated that dysregulation of …