CircGCN1L1 promotes synoviocyte proliferation and chondrocyte apoptosis by targeting miR-330-3p and TNF-α in TMJ osteoarthritis

H Zhu, Y Hu, C Wang, X Zhang, D He - Cell Death & Disease, 2020 - nature.com
Altered expression of circular RNAs (circRNAs) has been identified in various human
diseases. In this study, we investigated whether circRNAs function as competing …

Roles of circular RNAs in immune regulation and autoimmune diseases

Z Zhou, B Sun, S Huang, L Zhao - Cell death & disease, 2019 - nature.com
Circular RNAs (circRNAs), as a novel class of endogenously expressed non-coding RNAs
(ncRNAs), have a high stability and often present tissue-specific expression and …

CircPSMC3 suppresses the proliferation and metastasis of gastric cancer by acting as a competitive endogenous RNA through sponging miR-296-5p

D Rong, C Lu, B Zhang, K Fu, S Zhao, W Tang, H Cao - Molecular cancer, 2019 - Springer
Abstract Background Circular RNAs (circRNAs) are a class of non-coding RNAs with a loop
structure, but its functions remain largely unknown. Growing evidence has revealed that …

Roles of CircRNAs in autoimmune diseases

X Xia, X Tang, S Wang - Frontiers in Immunology, 2019 - frontiersin.org
Circular RNAs (circRNAs) are covalently linked single-stranded RNAs, compared to linear
counterparts that are relatively abundant, conserved, stable, and specific. Previously, most …

[HTML][HTML] Increased circulating circular RNA_103516 is a novel biomarker for inflammatory bowel disease in adult patients

YL Ye, J Yin, T Hu, LP Zhang, LY Wu… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Increasing evidence demonstrates that by acting as microRNA sponges
modulating gene expression at the transcriptional or post-transcriptional level, circular RNAs …

Circular noncoding RNAs as potential therapies and circulating biomarkers for cardiovascular diseases

AS Bayoumi, T Aonuma, J Teoh, Y Tang… - Acta Pharmacologica …, 2018 - nature.com
Recent advancements in genome-wide analyses and RNA-sequencing technologies led to
the discovery of small noncoding RNAs, such as microRNAs (miRs), as well as both linear …

Circular RNAs: from biogenesis and function to diseases

D Li, Y Yang, ZQ Li, LC Li, XH Zhu - Chinese Medical Journal, 2019 - journals.lww.com
Objective: Evidence suggests that various diseases may contribute to the circular RNAs
(circRNAs) expression disorder. This review was aimed at looking for appropriate …

CircRTN4 promotes pancreatic cancer progression through a novel CircRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein

CH Wong, UK Lou, FKC Fung, JHM Tong, C Zhang… - Molecular cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) play important roles in many biological
processes. However, the detailed mechanism underlying the critical roles of circRNAs in …

Hsa_circ_0046523 mediates an immunosuppressive tumor microenvironment by regulating MiR-148a-3p/PD-L1 axis in pancreatic cancer

X Fu, G Sun, S Tu, K Fang, Y Xiong, Y Tu, M Zha… - Frontiers in …, 2022 - frontiersin.org
Background Circular RNAs (circRNAs) are a novel type of non-coding RNA, play an
important role in the progression of tumors. However, the function and mechanism of …

Circular RNA expression profile and potential function of hsa_circ_0045272 in systemic lupus erythematosus

LJ Li, ZW Zhu, W Zhao, SS Tao, BZ Li, SZ Xu… - …, 2018 - Wiley Online Library
Circular RNA s (circRNAs) represent a class of non‐coding RNA s that form covalently
closed RNA circles with extensive expression and conservation in mammals. Circular RNA s …