Challenges and opportunities in developing targeted therapies for triple negative breast cancer

AG Chapdelaine, G Sun - Biomolecules, 2023 - mdpi.com
Triple negative breast cancer (TNBC) is a heterogeneous group of breast cancers
characterized by their lack of estrogen receptors, progesterone receptors, and the HER2 …

Molecular targets of triple-negative breast cancer: where do we stand?

EE Newton, LE Mueller, SM Treadwell, CA Morris… - Cancers, 2022 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is one of the most aggressive breast
cancer subtypes, largely due to heterogeneity and lack of treatment options. Due to absence …

Druggable molecular targets for the treatment of triple negative breast cancer

M Nakhjavani, JE Hardingham… - Journal of breast …, 2019 - synapse.koreamed.org
Breast cancer (BC) is still the most common cancer among women worldwide. Amongst the
subtypes of BC, triple negative breast cancer (TNBC) is characterized by deficient …

Pathogenesis and potential therapeutic targets for triple-negative breast cancer

CJ Li, YDT Tzeng, YH Chiu, HY Lin, MF Hou, PY Chu - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer emergencies have become a rapidly evolving field in
medicine during the last ten years. Carcinogenesis is a multiparametric process that …

Molecular targets and promising therapeutics of triple-negative breast cancer

WJ Ryu, JH Sohn - Pharmaceuticals, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most heterogeneous diseases in solid
tumors and has limited therapeutic options. Due to the lack of appropriate targetable …

[HTML][HTML] Recent therapeutic trends and promising targets in triple negative breast cancer

SY Hwang, S Park, Y Kwon - Pharmacology & therapeutics, 2019 - Elsevier
Breast cancer accounts for 25% of all types of cancer in women, and triple negative breast
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …

Recent advances in drug discovery for triple-negative breast cancer treatment

D Masci, C Naro, M Puxeddu, A Urbani, C Sette… - Molecules, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most heterogeneous and aggressive
breast cancer subtypes with a high risk of death on recurrence. To date, TNBC is very …

Concepts and targets in triple-negative breast cancer: recent results and clinical implications

P Saha, R Nanda - Therapeutic Advances in Medical …, 2016 - journals.sagepub.com
Triple-negative breast cancer (TNBC) is a heterogeneous disease in which tumors are
defined by lack of expression of the estrogen receptor (ER), the progesterone receptor (PR) …

Molecular Biology Mechanisms and Emerging Therapeutics of Triple-Negative Breast Cancer

Z Zhang, R Zhang, D Li - Biologics: Targets and Therapy, 2023 - Taylor & Francis
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is
conventionally characterized by the absence of estrogen receptor (ER), progesterone …

Current landscape of personalized clinical treatments for triple-negative breast cancer

J Zhang, Y Xia, X Zhou, H Yu, Y Tan, Y Du… - Frontiers in …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a highly malignant subtype of breast cancer (BC)
with vicious behaviors. TNBC is usually associated with relatively poor clinical outcomes …