Infections, cancer and autoimmune diseases occur more frequently in the elderly, and
although many factors contribute to this, the age-related remodelling of the immune system …

Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …

The aging immune system (immunosenescence) has been implicated with increased
morbidity and mortality in the elderly. Of note, T cell aging and low-grade inflammation …

Aging is associated with progressive loss of physiological integrity, leading to impaired
physical and mental functions as well as increased morbidity and mortality. With advancing …

Cellular senescence is a critical part of human anti-tumor defence; however, the
accumulation of senescent cells with age underpins a wide range of pathologies. Senescent …

Immunosenescence is the term commonly used to describe the multifaceted phenomenon
encompassing all changes occurring in the immune system during aging. It contributes to …

The aging process is associated with chronic low-grade inflammation in both humans and
rodents, commonly called inflammaging. At the same time, there is a gradual decline in the …

In the elderly, many alterations of innate and acquired immunity have been described and
viewed as deleterious, hence the term immunosenescence. Immunosenescence is a …

Immunosenescence is a term used to describe the age-related changes in the immune
system. Immunosenescence is associated with complex alterations and dysregulation of …

The innate immune system is composed of a network of cells including neutrophils, NK and
NKT cells, monocytes/macrophages, and dendritic cells that mediate the earliest interactions …