Immunosenescence resulting in decreased ability to control infectious disease contributes to
morbidity and mortality not only in the very elderly, but in all likelihood already from middle …

Immunosenescence contributes materially to the decreased ability of the elderly to control
infectious disease, which is also reflected in their generally poor response to vaccination …

As is apparent from the many contributions to this Special Issue of the Journal, the impact of
age on immunity is nefarious, with all manner of dysregulated responses attributed to …

Scientific progress in human immunosenescence research is pointing increasingly towards
the clinical importance of age-associated changes in immunity, although many areas remain …

The rapid growth in all aspects of immunological research in recent years has contributed
greatly to our un-derstanding of the mechanisms of immune senescence and the clinical …

Human immunosenescence contributes to morbidity and mortality in later life. The age-
associated increasing incidence ofcancer and cardiovascular disease plateaus at around 80 …

Accumulating data are documenting an inverse relationship between immune status,
response to vaccination, health, and longevity, suggesting that the immune system becomes …

As individuals age, dysfunction of the immune system leads to an increased incidence of
infectious disease. Due to the complex network of cellular interactions and the multi-factorial …

Understanding why we age and how that process can be delayed or reversed are topics that
have engaged both researchers and the general public [1]. From a scientific perspective …

An age‐related decline in immune functions, referred to as immunosenescence, is partially
responsible for the increased prevalence and severity of infectious diseases, and the low …