Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
Such testing and trying time probably never seen before in the human history. The novel
coronavirus disease abbreviated as COVID-19 is the ongoing health crisis which entered …

Immunobiology and immunotherapy of COVID‐19: A clinically updated overview

A Esmaeilzadeh, R Elahi - Journal of cellular physiology, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a new member of the
coronavirus family that can cause coronavirus disease 2019 (COVID‐19). COVID‐9 has …

Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients

I Convertino, M Tuccori, S Ferraro, G Valdiserra… - Critical Care, 2020 - Springer
Sars-CoV-2 complications include pneumonia and acute respiratory distress syndrome
(ARDS), which require intensive care unit admission. These conditions have rapidly …

Diverse manifestations of covid-19: Some suggested mechanisms

MS Zaman, RC Sizemore - … of Environmental Research and Public Health, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the novel
respiratory disease COVID-19, has reached pandemic status and presents a wide range of …

Applying lessons learned from COVID-19 therapeutic trials to improve future ALI/ARDS trials

Q Wu, ME Pennini, JN Bergmann… - Open Forum …, 2022 - academic.oup.com
Host-directed therapeutics targeting immune dysregulation are considered the most
promising approach to address the unmet clinical need for acute lung injury (ALI)/acute …

Potential therapeutic approaches for targeted inhibition of inflammatory cytokines following COVID-19 infection-induced cytokine storm

N Morgulchik, F Athanasopoulou, E Chu… - Interface …, 2021 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) is a deadly respiratory disease caused by severe
acute respiratory syndrome coronavirus 2, which has caused a global pandemic since early …

[HTML][HTML] Recent insight into SARS-CoV2 immunopathology and rationale for potential treatment and preventive strategies in COVID-19

S Lega, S Naviglio, S Volpi, A Tommasini - Vaccines, 2020 - mdpi.com
As the outbreak of the new coronavirus (SARS-CoV-2) infection is spreading globally, great
effort is being made to understand the disease pathogenesis and host factors that …

[HTML][HTML] Empirical treatment and prevention of COVID-19

HS Shin - Infection & chemotherapy, 2020 - ncbi.nlm.nih.gov
The rapid spread of severe acute respiratory coronavirus syndrome 2 (SARS-CoV-2) in the
population and throughout the cells within our body has been developing. Another major …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …