Xanthine oxidase (XO) is a crucial target for hyperuricemia treatment (s). Naturally occurred
XO inhibitors with minimal toxicity and high efficacy have attracted researchers' attention …

Two series of benzoflavone derivatives were rationally designed, synthesized and evaluated
for their xanthine oxidase (XO) inhibitory potential. Among both series, eight compounds (NF …

Xanthine oxidase (XO) is a crucial target for the treatment of hyperuricemia and gout. A
series of derivatives based on natural 3, 4-dihydroxychalcone, obtained from Carthamus …

Aim and Objective: The present study was designed to evaluate the xanthine oxidase (XO)
inhibitory and antioxidant activities of 30 bioactive compounds present in edible food plants …

Xanthine oxidase (XO) is a key enzyme in the generation and development of
hyperuricemia. Thiazolidine-2-thione, a typical heterocyclic compound, have been widely …

Excessive intake of purine-rich foods such as seafood and red meat leads to excess
xanthine oxidase activity and provokes gout attacks. The aim of this paper is to evaluate in …

Background: Xanthine oxidase is an important enzyme which catalyzes the production of
uric acid and superoxide anion from xanthine. The over-production of these products leads …

Xanthine oxidase (XO) is an interesting target for the synergic treatment of several diseases.
Coumarin scaffold plays an important role in the design of efficient and potent inhibitors. In …

Hyperuricemia (HUA), an abnormally high level of uric acid (UA) in the blood, is showing an
increasing incidence and younger tendency worldwide. Xanthine oxidase (XO) inhibitors …

This project was designed to explore the xanthine oxidase (XO) inhibitory mechanism of
eight structurally diverse phenolic compounds [quercetin: C1, quercetin-3-rhamnoside: C2 …