Kidney development starts with an epithelial bud and a domain of committed mesenchyme
inducing one another so that the former gives a bifurcating duct system and the latter …

Embryonic kidney is ideal for the study of epithelial morphogenesis—rich in developmental
processes, accessible and clinically important. Interactions between mesenchyme and the …

The development of the mature mammalian kidney begins with the invasion of metanephric
mesenchyme by ureteric bud. Mesenchymal cells near the bud become induced and convert …

Although it is not easy to investigate the regulatory basis of developmental processes in
most mammalian tissues, the mouse kidney has several distinct advantages as a model …

For more than 40 years now, the developing kidney has served as a model paradigm for
epithelial‐mesenchymal interactions. The principles of inductive signaling, epithelial cell …

Development of an organ is directed by cell and tissue interactions and these also occur
during the formation of functional kidney. During vertebrate development inductive signalling …

In Mammals, kidney development proceeds in three stages (reviewed in 1). The first two
stages lead to the formation of transient structures, the pronephros and the mesonephros …

As in most organs, the emerging theme in kidney development is the importance of cross-
talk between several tissues and cell lineages to allow morphogenesis to proceed in a …

The mammalian kidney is a vital organ with considerable cellular complexity and functional
diversity. Kidney development is notable for requiring distinct but coincident tubulogenic …

The kidney plays an essential role during excretion of metabolic waste products,
maintenance of key homeostasis components such as ion concentrations and hormone …