Cytokines in atherosclerosis: pathogenic and regulatory pathways

A Tedgui, Z Mallat - Physiological reviews, 2006 - journals.physiology.org
Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Recent advances on the role of cytokines in atherosclerosis

H Ait-Oufella, S Taleb, Z Mallat… - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and
adaptive immune responses. Inflammation controls the development and the destabilization …

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

The role of cytokines in the development of atherosclerosis

AR Fatkhullina, IO Peshkova, EK Koltsova - Biochemistry (Moscow), 2016 - Springer
Atherosclerosis contributes to the development of many cardiovascular diseases, which
remain the leading cause of death in developed countries. Atherosclerosis is a chronic …

Cytokines and atherosclerosis: a comprehensive review of studies in mice

R Kleemann, S Zadelaar, T Kooistra - Cardiovascular research, 2008 - academic.oup.com
In the past few years, inflammation has emerged as a major driving force of atherosclerotic
lesion development. It is now well-established that from early lesion to vulnerable plaque …

Inflammation and atherosclerosis: a review of the role of interleukin-6 in the development of atherosclerosis and the potential for targeted drug therapy

J Hartman, WH Frishman - Cardiology in review, 2014 - journals.lww.com
It has recently been appreciated that atherosclerosis is predominantly an inflammatory
process. Atherosclerosis begins with a fatty streak, which is made up almost entirely of …

Cytokines in the pathogenesis of atherosclerosis

JL Young, P Libby, U Schönbeck - Thrombosis and …, 2002 - thieme-connect.com
Research during the last two decades established atheromatous lesions as active sites of
inflammation and immune responses, contrasting to the traditional view of atherosclerosis as …

Interleukins in atherosclerosis: molecular pathways and therapeutic potential

JH Von der Thüsen, J Kuiper, TJC Van Berkel… - Pharmacological …, 2003 - ASPET
Interleukins are considered to be key players in the chronic vascular inflammatory response
that is typical of atherosclerosis. Thus, the expression of proinflammatory interleukins and …

How much is too much? Interleukin-6 and its signalling in atherosclerosis

H Schuett, M Luchtefeld, C Grothusen… - Thrombosis and …, 2009 - thieme-connect.com
The importance of inflammation as a driver of pathology is no longer confined to
autoimmune and infectious diseases. In line with convincing experimental data as well as …