Host genetic basis of COVID-19: from methodologies to genes

K Zguro, C Fallerini, F Fava, S Furini… - European Journal of …, 2022 - nature.com
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) is having a massive impact on public health, societies, and economies …

[HTML][HTML] Genetic susceptibility to severe COVID-19

C Cappadona, V Rimoldi, EM Paraboschi… - Infection, Genetics and …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of the
coronavirus disease 2019 (COVID-19) pandemic. Clinical manifestations of the disease …

COVID-19 annual update: a narrative review

M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity

C Anastassopoulou, Z Gkizarioti, GP Patrinos… - Human genomics, 2020 - Springer
Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

Identification of human genetic variants modulating the course of COVID-19 infection with importance in other viral infections

L Salihefendić, I Čeko, L Bešić… - Frontiers in …, 2023 - frontiersin.org
Introduction: COVID-19 has been a major focus of scientific research since early 2020. Due
to its societal, economic, and clinical impact worldwide, research efforts aimed, among other …

The COVID-19 host genetics initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic

COVID-19 Host Genetics Initiative aganna … - European Journal of …, 2020 - nature.com
The COVID-19 pandemic is a global crisis creating severe disruptions across the economy
and health system. Insights into how to better understand and treat COVID-19 are …

The human genetic epidemiology of COVID-19

MEK Niemi, MJ Daly, A Ganna - Nature Reviews Genetics, 2022 - nature.com
Human genetics can inform the biology and epidemiology of coronavirus disease 2019
(COVID-19) by pinpointing causal mechanisms that explain why some individuals become …

COVID-19 and SARS-CoV-2 variants: current challenges and health concern

M Zeyaullah, AM AlShahrani, K Muzammil… - Frontiers in …, 2021 - frontiersin.org
The ongoing coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, was
triggered and unfolded quickly throughout the globe by severe acute respiratory syndrome …

The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

COVID-19 outcomes and the human genome

MF Murray, EE Kenny, MD Ritchie, DJ Rader… - Genetics in …, 2020 - nature.com
BACKGROUND In the COVID-19 pandemic, the opportunity to link host genomic factors to
the highly variable clinical manifestations of SARS-CoV-2 infection has been widely …