Omega-3 fatty acids and cardiovascular disease: are there benefits?

KJ Bowen, WS Harris, PM Kris-Etherton - Current treatment options in …, 2016 - Springer
Opinion statement Early secondary prevention trials of fish and omega-3 polyunsaturated
fatty acid (PUFA) capsules reported beneficial effects on cardiovascular disease (CVD) …

Omega-3 polyunsaturated fatty acids and cardiovascular diseases

CJ Lavie, RV Milani, MR Mehra, HO Ventura - Journal of the American …, 2009 - jacc.org
Omega-3 polyunsaturated fatty acid (ω-3 PUFA) therapy continues to show great promise in
primary and, particularly in secondary prevention of cardiovascular (CV) diseases. The most …

Omega-3 polyunsaturated fatty acids focusing on eicosapentaenoic acid and docosahexaenoic acid in the prevention of cardiovascular diseases: a review of the state …

Y Watanabe, I Tatsuno - Expert Review of Clinical Pharmacology, 2021 - Taylor & Francis
Introduction: An epidemiological study of Greenlandic Inuit suggested the importance of
omega-3 polyunsaturated fatty acids (PUFAs) in preventing ischemic heart disease. After …

Omega-3 polyunsaturated fatty acids supplementation and cardiovascular outcomes: do formulation, dosage, and baseline cardiovascular risk matter? An updated …

M Casula, E Olmastroni, M Gazzotti, F Galimberti… - Pharmacological …, 2020 - Elsevier
The recent publication of the REDUCE-IT study has reopened the debate about the efficacy
of omega-3 fatty acids in reducing the risk of cardiovascular (CV) events. This meta-analysis …

Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis

EC Rizos, EE Ntzani, E Bika, MS Kostapanos… - Jama, 2012 - jamanetwork.com
Context Considerable controversy exists regarding the association of omega-3
polyunsaturated fatty acids (PUFAs) and major cardiovascular end points. Objective To …

Omega-3 polyunsaturated fatty acids for cardiovascular diseases: present, past and future

Y Watanabe, I Tatsuno - Expert Review of Clinical Pharmacology, 2017 - Taylor & Francis
Introduction: Large-scale epidemiological studies on Greenlandic, Canadian and Alaskan
Eskimos have examined the health benefits of omega-3 fatty acids consumed as part of the …

Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids: JACC Focus Seminar

RL Weinberg, RD Brook, M Rubenfire… - Journal of the American …, 2021 - jacc.org
Omega-3 polyunsaturated fatty acids (PUFAs) are a key component of a heart-healthy diet.
For patients without clinical atherosclerotic cardiovascular disease, 2 or more servings of …

Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events

D Mozaffarian, JHY Wu - Journal of the American College of Cardiology, 2011 - jacc.org
We reviewed available evidence for cardiovascular effects of n-3 polyunsaturated fatty acid
(PUFA) consumption, focusing on long chain (seafood) n-3 PUFA, including their principal …

Omega‐3 polyunsaturated fatty acids: the way forward in times of mixed evidence

KH Weylandt, S Serini, YQ Chen, HM Su… - BioMed research …, 2015 - Wiley Online Library
Almost forty years ago, it was first hypothesized that an increased dietary intake of omega‐3
polyunsaturated fatty acids (PUFA) from fish fat could exert protective effects against several …

Omega-3 polyunsaturated fatty acid (fish oil) supplementation and the prevention of clinical cardiovascular disease: a science advisory from the American Heart …

DS Siscovick, TA Barringer, AM Fretts, JHY Wu… - Circulation, 2017 - Am Heart Assoc
Multiple randomized controlled trials (RCTs) have assessed the effects of supplementation
with eicosapentaenoic acid plus docosahexaenoic acid (omega-3 polyunsaturated fatty …