Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pathogen of immense
public health concern. Efforts to control the disease have only proven mildly successful, and …

The 2019 novel coronavirus, SARS-CoV-2, is an emerging pathogen of critical significance
to international public health. Knowledge of the interplay between molecular-scale virus …

The scientific community is focussed on developing antiviral therapies to mitigate the
impacts of the ongoing novel coronavirus disease (COVID-19) outbreak. This will be …

Within‐host model specified by viral dynamic parameters is a mainstream tool to understand
SARS‐CoV‐2 replication cycle in infected patients. The parameter uncertainty further affects …

Within-host models of COVID-19 infection dynamics enable the merits of different forms of
antiviral therapy to be assessed in individual patients. A stochastic agent-based model of …

Relationships between viral load, severity of illness, and transmissibility of virus are
fundamental to understanding pathogenesis and devising better therapeutic and prevention …

Understanding the underlying mechanisms of COVID-19 progression and the impact of
various pharmaceutical interventions is crucial for the clinical management of the disease …

The scientific community is focused on developing antiviral therapies to mitigate the impacts
of the ongoing novel coronavirus disease 2019 (COVID-19) outbreak. This will be facilitated …

SARS-CoV-2 is a human pathogen that causes infection in both the upper respiratory tract
(URT) and the lower respiratory tract (LRT). The viral kinetics of SARS-CoV-2 infection and …

Virus-host interactions can reveal potentially effective and selective therapeutic targets for
treating infection. Here, we performed an integrated analysis of the dynamics of virus …