SARS-CoV-2 antibody avidity responses in COVID-19 patients and convalescent plasma donors

SE Benner, EU Patel, O Laeyendecker… - The Journal of …, 2020 - academic.oup.com
Background Convalescent plasma therapy is a leading treatment for conferring temporary
immunity to COVID-19–susceptible individuals or for use as post-exposure prophylaxis …

Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response

M Marconato, IA Abela, A Hauser… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND Neutralizing antibodies are considered a key correlate of protection by
current SARS-CoV-2 vaccines. The manner in which human infections respond to …

Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID‐19 convalescent plasma clinical trial

MLL Madariaga, JJ Guthmiller… - Journal of internal …, 2021 - Wiley Online Library
Background Convalescent plasma therapy for COVID‐19 relies on transfer of anti‐viral
antibody from donors to recipients via plasma transfusion. The relationship between clinical …

Clinical, laboratory, and temporal predictors of neutralizing antibodies against SARS-CoV-2 among COVID-19 convalescent plasma donor candidates

J Boonyaratanakornkit, C Morishima… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND SARS-CoV-2–specific antibodies may protect from reinfection and disease,
providing rationale for administration of plasma containing SARS-CoV-2–neutralizing …

Disease severity, fever, age, and sex correlate with SARS-CoV-2 neutralizing antibody responses

S Schlickeiser, T Schwarz, S Steiner, K Wittke… - Frontiers in …, 2021 - frontiersin.org
Clinical trials on the use of COVID-19 convalescent plasma remain inconclusive. While data
on safety is increasingly available, evidence for efficacy is still sparse. Subgroup analyses …

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population

SL Klein, A Pekosz, HS Park, RL Ursin… - The Journal of …, 2020 - Am Soc Clin Investig
Convalescent plasma is a leading treatment for coronavirus disease 2019 (COVID-19), but
there is a paucity of data identifying its therapeutic efficacy. Among 126 potential …

Anti–SARS-CoV-2 antibody responses in convalescent plasma donors are increased in hospitalized patients; subanalyses of a phase 2 clinical study

E Terpos, M Politou, TN Sergentanis, A Mentis… - Microorganisms, 2020 - mdpi.com
We evaluated the antibody responses in 259 potential convalescent plasma donors for
Covid-19 patients. Different assays were used: a commercial ELISA detecting antibodies …

[HTML][HTML] Relationship between anti-spike protein antibody titers and SARS-CoV-2 in vitro virus neutralization in convalescent plasma

E Salazar, SV Kuchipudi, PA Christensen, TN Eagar… - biorxiv, 2020 - ncbi.nlm.nih.gov
Newly emerged pathogens such as SARS-CoV-2 highlight the urgent need for assays that
detect levels of neutralizing antibodies that may be protective. We studied the relationship …

SARS‐CoV‐2 antibody persistence in COVID‐19 convalescent plasma donors: dependency on assay format and applicability to serosurveillance

C Di Germanio, G Simmons, K Kelly, R Martinelli… - …, 2021 - Wiley Online Library
Background Antibody response duration following severe acute respiratory syndrome
coronavirus 2 infection tends to be variable and depends on severity of disease and method …

Decline of humoral responses against SARS-CoV-2 spike in convalescent individuals

G Beaudoin-Bussières, A Laumaea, SP Anand… - MBio, 2020 - Am Soc Microbiol
In the absence of effective vaccines and with limited therapeutic options, convalescent
plasma is being collected across the globe for potential transfusion to coronavirus disease …