The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …

Inflammatory bowel disease: a potential result from the collusion between gut microbiota and mucosal immune system

B Yue, X Luo, Z Yu, S Mani, Z Wang, W Dou - Microorganisms, 2019 - mdpi.com
Host health depends on the intestinal homeostasis between the innate/adaptive immune
system and the microbiome. Numerous studies suggest that gut microbiota are constantly …

The interplay between host immune cells and gut microbiota in chronic inflammatory diseases

D Kim, MY Zeng, G Núñez - Experimental & molecular medicine, 2017 - nature.com
Many benefits provided by the gut microbiota to the host rely on its intricate interactions with
host cells. Perturbations of the gut microbiota, termed gut dysbiosis, affect the interplay …

The interplay between microbes and the immune response in inflammatory bowel disease

A Goethel, K Croitoru, DJ Philpott - The Journal of physiology, 2018 - Wiley Online Library
The aetiology and pathogenesis of inflammatory bowel disease (IBD) remains unclear but
involves a complex interplay between genetic risk, environmental exposures, the immune …

Microbiome and gut dysbiosis

JE Belizário, J Faintuch - Metabolic interaction in infection, 2018 - Springer
The gastrointestinal (GI) tract is the residence of trillions of microorganisms that include
bacteria, archaea, fungi and viruses. The collective genomes of whole microbial …

Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome

I Khan, N Ullah, L Zha, Y Bai, A Khan, T Zhao, T Che… - Pathogens, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …

Etiopathogenesis of inflammatory bowel disease: today and tomorrow

HSP de Souza - Current opinion in gastroenterology, 2017 - journals.lww.com
The continuing identification of several epigenetic, transcriptomic, proteomic, and
metabolomic alterations in patients with IBD reflects the complex nature of the disease and …

Gut microbiome in chronic rheumatic and inflammatory bowel diseases: Similarities and differences

F Salem, N Kindt, JR Marchesi… - United European …, 2019 - journals.sagepub.com
Introduction Inflammatory bowel diseases (IBDs) and chronic rheumatic diseases (CRDs)
are systemic chronic disorders sharing common genetic, immune and environmental factors …

The microbiota and inflammatory bowel disease: insights from animal models

JM Peloquin, DD Nguyen - Anaerobe, 2013 - Elsevier
Inflammatory bowel disease (IBD) is thought to result from a dysregulated immune response
to intestinal microbial flora in individuals with genetic predisposition (s). Genome-wide …

Genetic factors and the intestinal microbiome guide development of microbe-based therapies for inflammatory bowel diseases

LJ Cohen, JH Cho, D Gevers, H Chu - Gastroenterology, 2019 - Elsevier
The intestinal microbiota is a dynamic community of bacteria, fungi, and viruses that
mediates mucosal homeostasis and physiology. Imbalances in the microbiome and aberrant …