B Yue, X Luo, Z Yu, S Mani, Z Wang, W Dou - Microorganisms, 2019 - mdpi.com
Host health depends on the intestinal homeostasis between the innate/adaptive immune system and the microbiome. Numerous studies suggest that gut microbiota are constantly …
D Kim, MY Zeng, G Núñez - Experimental & molecular medicine, 2017 - nature.com
Many benefits provided by the gut microbiota to the host rely on its intricate interactions with host cells. Perturbations of the gut microbiota, termed gut dysbiosis, affect the interplay …
A Goethel, K Croitoru, DJ Philpott - The Journal of physiology, 2018 - Wiley Online Library
The aetiology and pathogenesis of inflammatory bowel disease (IBD) remains unclear but involves a complex interplay between genetic risk, environmental exposures, the immune …
The gastrointestinal (GI) tract is the residence of trillions of microorganisms that include bacteria, archaea, fungi and viruses. The collective genomes of whole microbial …
I Khan, N Ullah, L Zha, Y Bai, A Khan, T Zhao, T Che… - Pathogens, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …
HSP de Souza - Current opinion in gastroenterology, 2017 - journals.lww.com
The continuing identification of several epigenetic, transcriptomic, proteomic, and metabolomic alterations in patients with IBD reflects the complex nature of the disease and …
JM Peloquin, DD Nguyen - Anaerobe, 2013 - Elsevier
Inflammatory bowel disease (IBD) is thought to result from a dysregulated immune response to intestinal microbial flora in individuals with genetic predisposition (s). Genome-wide …
LJ Cohen, JH Cho, D Gevers, H Chu - Gastroenterology, 2019 - Elsevier
The intestinal microbiota is a dynamic community of bacteria, fungi, and viruses that mediates mucosal homeostasis and physiology. Imbalances in the microbiome and aberrant …