Current understanding of microbiota-and dietary-therapies for treating inflammatory bowel disease

T Eom, YS Kim, CH Choi, MJ Sadowsky, T Unno - Journal of Microbiology, 2018 - Springer
Inflammatory bowel disease (IBD) is a result of chronic inflammation caused, in some part,
by dysbiosis of intestinal microbiota, mainly commensal bacteria. Gut dysbiosis can be …

Microbial host interactions in IBD: implications for pathogenesis and therapy

R Balfour Sartor, M Muehlbauer - Current gastroenterology reports, 2007 - Springer
Abstract Crohn's disease (CD), ulcerative colitis (UC), and pouchitis appear to be caused by
pathogenic T-cell responses to discrete antigens from the complex luminal microbiota, with …

Mechanisms and consequences of intestinal dysbiosis

GA Weiss, T Hennet - Cellular and Molecular Life Sciences, 2017 - Springer
The composition of the gut microbiota is in constant flow under the influence of factors such
as the diet, ingested drugs, the intestinal mucosa, the immune system, and the microbiota …

Therapeutic opportunities in inflammatory bowel disease: mechanistic dissection of host-microbiome relationships

DR Plichta, DB Graham, S Subramanian, RJ Xavier - Cell, 2019 - cell.com
The current understanding of inflammatory bowel disease (IBD) pathogenesis implicates a
complex interaction between host genetics, host immunity, microbiome, and environmental …

[HTML][HTML] Can control of gut microbiota be a future therapeutic option for inflammatory bowel disease?

A Nishida, K Nishino, K Sakai, Y Owaki… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract encompassing two main clinical entities, Crohn's disease and ulcerative colitis …

The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new …

SM Vindigni, TL Zisman, DL Suskind… - Therapeutic …, 2016 - journals.sagepub.com
We discuss the tripartite pathophysiological circuit of inflammatory bowel disease (IBD),
involving the intestinal microbiota, barrier function, and immune system. Dysfunction in each …

[HTML][HTML] Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models

E Mizoguchi, D Low, Y Ezaki, T Okada - Intestinal research, 2020 - synapse.koreamed.org
The specific pathogenesis underlining inflammatory bowel disease (IBD) is very
complicated, and it is further more difficult to clearly explain the pathophysiology of 2 major …

[HTML][HTML] The gut microbiome and irritable bowel syndrome

S Menees, W Chey - F1000Research, 2018 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal
disorders encountered in clinical practice. It is a heterogeneous disorder with a multifactorial …

Bacterial species associated with human inflammatory bowel disease and their pathogenic mechanisms

L Zhang, F Liu, J Xue, SA Lee, L Liu… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract with unknown etiology. The pathogenesis of IBD results from immune responses to …

The gut microbiota in immune-mediated inflammatory diseases

JD Forbes, G Van Domselaar… - Frontiers in microbiology, 2016 - frontiersin.org
The collection of microbes and their genes that exist within and on the human body,
collectively known as the microbiome has emerged as a principal factor in human health …