Effect of discontinuation of growth hormone treatment on risk factors for cardiovascular disease in adolescents born small for gestational age

Y van Pareren, P Mulder, M Houdijk… - The Journal of …, 2003 - academic.oup.com
Hyperlipidemia, diabetes mellitus type 2, and coronary heart disease have been associated
with being born small for gestational age (SGA). It has been reported that GH treatment …

Risk factors for diabetes mellitus type 2 and metabolic syndrome are comparable for previously growth hormone-treated young adults born small for gestational age …

M Van Dijk, EMN Bannink… - The Journal of …, 2007 - academic.oup.com
Context: Low birth weight might increase risk of diabetes mellitus type 2 and metabolic
syndrome (MS). GH has insulin-antagonistic properties. Therefore, long-term follow-up of …

The effect of growth hormone treatment on metabolic and cardiovascular risk factors is similar in preterm and term short, small for gestational age children

SWK De Kort, RH Willemsen… - Clinical …, 2009 - Wiley Online Library
Context We previously reported that short, small for gestational age (SGA) children who
were born preterm have a lower body fat percentage and a higher blood pressure, insulin …

The influence of a long-term growth hormone treatment on lipid and glucose metabolism: a randomized trial in short Japanese children born small for gestational age

R Horikawa, T Tanaka, H Nishinaga, Y Ogawa… - International Journal of …, 2016 - Springer
Background Long-term growth hormone (GH) treatments in short children born small for
gestational age (SGA) restore lipid metabolism, but also increase insulin resistance. The aim …

Small for gestational age (SGA): endocrine and metabolic consequences and effects of growth hormone treatment.

AC Hokken-Koelega, WJ De Waal, TC Sas… - Journal of Pediatric …, 2004 - europepmc.org
Several studies have demonstrated an association between low birth weight and impaired
insulin sensitivity or even type 2 diabetes mellitus (DM2) in later life. Growth hormone (GH) …

Body composition, blood pressure, and lipid metabolism before and during long-term growth hormone (GH) treatment in children with short stature born small for …

T Sas, P Mulder… - The Journal of Clinical …, 2000 - academic.oup.com
To assess the effects of long-term continuous GH treatment on body composition, blood
pressure (BP), and lipid metabolism in children with short stature born small for gestational …

Final height data, body composition and glucose metabolism in growth hormone-treated short children born small for gestational age

ACS Hokken-Koelega, Y van Pareren, T Sas… - Hormone …, 2003 - karger.com
Abstract Extended Abstract Low birth weight has been associated with impaired insulin
sensitivity, type 2 diabetes mellitus, hypertension and cardiovascular disease in later life. GH …

The impact of long-term growth hormone treatment on metabolic parameters in Japanese patients with short stature born small for gestational age

AM Kappelgaard, F Kiyomi, R Horikawa… - Hormone Research in …, 2014 - karger.com
Abstract Background/Aims: An examination of the effects of up to 260 weeks of growth
hormone (GH) therapy on metabolic parameters in Japanese children born small for …

Longitudinal changes in insulin sensitivity and body composition of small-for-gestational-age adolescents after cessation of growth hormone treatment

RH Willemsen, SP Willemsen… - The Journal of …, 2008 - academic.oup.com
Context: GH treatment reduces insulin sensitivity (Si). For small-for-gestational-age (SGA)
subjects, who might have an increased risk to develop cardiovascular disease and type 2 …

Metabolic health in short children born small for gestational age treated with growth hormone and gonadotropin-releasing hormone analog: results of a randomized …

M van der Steen, AJ Lem… - The Journal of …, 2015 - academic.oup.com
Context: Previously we showed that pubertal children born small for gestational age (SGA)
with a poor adult height (AH) expectation can benefit from treatment with GH 1 mg/m2 per …