[HTML][HTML] COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning

E Ong, MU Wong, A Huffman, Y He - Frontiers in immunology, 2020 - frontiersin.org
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective
and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 …

[HTML][HTML] Reverse vaccinology assisted designing of multiepitope-based subunit vaccine against SARS-CoV-2

M Tahir ul Qamar, F Shahid, S Aslam… - Infectious diseases of …, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) linked with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) cause severe illness and life-threatening …

[HTML][HTML] Immunoinformatic analysis of T-and B-cell epitopes for SARS-CoV-2 vaccine design

D Wang, J Mai, W Zhou, W Yu, Y Zhan, N Wang… - Vaccines, 2020 - mdpi.com
Currently, there is limited knowledge about the immunological profiles of Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We used computer-based …

Artificial intelligence‐based data‐driven strategy to accelerate research, development, and clinical trials of COVID vaccine

A Sharma, T Virmani, V Pathak… - BioMed research …, 2022 - Wiley Online Library
The global COVID‐19 (coronavirus disease 2019) pandemic, which was caused by the
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has resulted in a …

[HTML][HTML] Designing multi-epitope vaccines to combat emerging coronavirus disease 2019 (COVID-19) by employing immuno-informatics approach

A Naz, F Shahid, TT Butt, FM Awan, A Ali… - Frontiers in …, 2020 - frontiersin.org
A recent pandemic caused by a single-stranded RNA virus, COVID-19, initially discovered in
China, is now spreading globally. This poses a serious threat that needs to be addressed …

[HTML][HTML] An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study

Z Yang, P Bogdan, S Nazarian - Scientific reports, 2021 - nature.com
The rampant spread of COVID-19, an infectious disease caused by SARS-CoV-2, all over
the world has led to over millions of deaths, and devastated the social, financial and political …

[PDF][PDF] The immunodominant and neutralization linear epitopes for SARS-CoV-2

S Lu, X Xie, L Zhao, B Wang, J Zhu, T Yang, G Yang… - Cell reports, 2021 - cell.com
Although vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
are under development, the antigen epitopes on the virus and their immunogenicity are …

Reverse vaccinology approach to design a novel multi-epitope vaccine candidate against COVID-19: an in silico study

M Enayatkhani, M Hasaniazad, S Faezi… - Journal of …, 2021 - Taylor & Francis
Abstract At present, novel Coronavirus (2019-nCoV, the causative agent of COVID-19) has
caused worldwide social and economic disruption. The disturbing statistics of this infection …

[HTML][HTML] In silico identification of vaccine targets for 2019-nCoV

CH Lee, H Koohy - F1000Research, 2020 - ncbi.nlm.nih.gov
Background: The newly identified coronavirus known as 2019-nCoV has posed a serious
global health threat. According to the latest report (18-February-2020), it has infected more …

[HTML][HTML] The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines

W Shang, Y Yang, Y Rao, X Rao - npj Vaccines, 2020 - nature.com
The outbreak of 2019-novel coronavirus disease (COVID-19) that is caused by SARS-CoV-2
has spread rapidly in China, and has developed to be a Public Health Emergency of …