Preliminary predictive criteria for COVID-19 cytokine storm

R Caricchio, M Gallucci, C Dass, X Zhang… - Annals of the …, 2021 - ard.bmj.com
Objectives To develop predictive criteria for COVID-19-associated cytokine storm (CS), a
severe hyperimmune response that results in organ damage in some patients infected with …

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate

P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

[PDF][PDF] Discrimination of COVID‐19 from inflammation‐induced cytokine storm syndromes using disease‐related blood biomarkers

C Kessel, R Vollenberg… - Arthritis & …, 2021 - Wiley Online Library
Objective Infection with the novel coronavirus SARS–CoV‐2 triggers severe illness with high
mortality in a subgroup of patients. Such a critical course of COVID‐19 is thought to be …

COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study

JJ Manson, C Crooks, M Naja, A Ledlie… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with severe COVID-19 develop a hyperinflammatory
syndrome, which might contribute to morbidity and mortality. This study explores a specific …

On the alert for cytokine storm: immunopathology in COVID‐19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
Poor outcomes in COVID‐19 correlate with clinical and laboratory features of cytokine storm
syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy …

Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study

BJ Webb, ID Peltan, P Jensen, D Hoda… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with COVID-19 develops a hyperinflammatory syndrome
that has similarities with other hyperinflammatory disorders. However, clinical criteria …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

The rheumatologist's role in COVID-19

RQ Cron, WW Chatham - The Journal of rheumatology, 2020 - jrheum.org
The novel coronavirus (severe acute respiratory syndrome; SARS-CoV-2) pandemic has
spread rapidly throughout the planet. It is believed to have originated in the Wuhan province …

Basic predictive risk factors for cytokine storms in COVID-19 patients

SG Shcherbak, AY Anisenkova, SV Mosenko… - Frontiers in …, 2021 - frontiersin.org
Objective A critical role in coronavirus disease 2019 (COVID-19) pathogenesis is played by
immune dysregulation that leads to a generalized uncontrolled multisystem inflammatory …

Laboratory trends, hyperinflammation, and clinical outcomes for patients with a systemic rheumatic disease admitted to hospital for COVID-19: a retrospective …

TYT Hsu, KM D'Silva, NJ Patel, J Wang… - The Lancet …, 2021 - thelancet.com
Background COVID-19 can induce a hyperinflammatory state, which might lead to poor
clinical outcomes. We aimed to assess whether patients with a systemic rheumatic disease …