Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 9.2 million …

Therapeutic role of immunomodulators during the COVID-19 pandemic–a narrative review

H Al-Hajeri, F Baroun, F Abutiban… - Postgraduate …, 2022 - Taylor & Francis
The emergency state caused by COVID-19 saw the use of immunomodulators despite the
absence of robust research. To date, the results of relatively few randomized controlled trials …

Inflammatory pathways and potential therapies for COVID-19: A mini review

AM Dabbish, N Yonis, M Salama… - European Journal …, 2021 - journals.sagepub.com
The public health crisis of the novel coronavirus disease (COVID-19) is alarming since
January 2020. COVID-19 genome (SARS-CoV-2) is related to other highly pathogenic …

Chemotherapy vs. Immunotherapy in combating nCOVID19: An update

A Choudhury, G Mukherjee, S Mukherjee - Human Immunology, 2021 - Elsevier
The nCOVID-19 pandemic initiated its course of contagion from the city of Wuhan and now it
has spread all over the globe. SARS-CoV-2 is the causative virus and the infection as well …

[HTML][HTML] Macrophage activation and cytokine release syndrome in COVID-19: current updates and analysis of repurposed and investigational anti-cytokine drugs

A Iqubal, F Hoda, AK Najmi, SE Haque - Drug Research, 2021 - thieme-connect.com
Coronavirus disease (COVID-19) emerged from Wuhan, has now become pandemic and
the mortality rate is growing exponentially. Clinical complication and fatality rate is much …

[HTML][HTML] Current status of therapeutic alternatives for COVID-19: A narrative review

AT Aslan, M Akova - Le infezioni in medicina, 2021 - ncbi.nlm.nih.gov
Since December 2019, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection has exploded and led to a global crisis. Currently, the global case numbers topped …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

COVID-19 as an acute inflammatory disease

RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
Abstract The 2019 coronavirus disease (COVID-19) pandemic caused by the virus severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

Influenza infection, SARS, MERS and COVID-19: cytokine storm–the common denominator and the lessons to be learned

VA Ryabkova, LP Churilov, Y Shoenfeld - Clinical Immunology, 2021 - Elsevier
The outbreak of COVID-19 reminds us that the emerging and reemerging respiratory virus
infections pose a continuing threat to human life. Cytokine storm syndromes of viral origin …