Cardiovascular complications of down syndrome: scoping review and expert consensus

K Dimopoulos, A Constantine, P Clift, R Condliffe… - Circulation, 2023 - Am Heart Assoc
Cardiovascular disease is a leading cause of morbidity and mortality in individuals with
Down syndrome. Congenital heart disease is the most common cardiovascular condition in …

Dynamics in prevalence of Down syndrome in children with congenital heart disease

C Pfitzer, PC Helm, LM Rosenthal, F Berger… - European journal of …, 2018 - Springer
We assessed the dynamics in the prevalence of children with congenital heart disease
(CHD) and Down syndrome in Germany with regard to phenotype, severity, and gender …

Congenital heart disease in Down syndrome–A review of temporal changes

SL Santoro, EH Steffensen - Journal of Congenital Cardiology, 2021 - Springer
Background Congenital heart disease (CHD) is a well-known co-occurring condition in
Down syndrome (DS). We aimed to review the literature to evaluate the current evidence to …

Cardiovascular abnormalities in Down's syndrome: spectrum, management and survival over 22 years

CA Irving, MP Chaudhari - Archives of disease in childhood, 2012 - adc.bmj.com
Background The prevalence of cardiovascular anomalies in Down's syndrome is well
described, but there are few data on spectrum, management and outcome. The authors …

Trends in congenital heart defects in infants with Down syndrome

S Bergström, H Carr, G Petersson, O Stephansson… - …, 2016 - publications.aap.org
BACKGROUND: As a result of antenatal screening, abortion of fetuses with Down syndrome
has become increasingly common. Little is known about the cardiovascular phenotype in …

Cardiovascular disease in Down syndrome

P Versacci, D Di Carlo, MC Digilio… - Current opinion in …, 2018 - journals.lww.com
Cardiovascular disease in Down syndrome : Current Opinion in Pediatrics Cardiovascular
disease in Down syndrome : Current Opinion in Pediatrics Log in or Register Subscribe to …

Association between Down syndrome and in-hospital death among children undergoing surgery for congenital heart disease: a US population-based study

JM Evans, M Dharmar, E Meierhenry… - … Quality and Outcomes, 2014 - Am Heart Assoc
Background—The prevalence of Down syndrome (DS)–affected births has increased during
the past 30 years; moreover, children with DS have a higher incidence of congenital heart …

Down syndrome and congenital heart disease: perioperative planning and management

DR Delany, SS Gaydos, DA Romeo… - Journal of Congenital …, 2021 - Springer
Approximately 50% of newborns with Down syndrome have congenital heart disease. Non-
cardiac comorbidities may also be present. Many of the principles and strategies of …

Infants born with Down syndrome: burden of disease in the early neonatal period

T Martin, A Smith, CR Breatnach, E Kent… - The Journal of …, 2018 - Elsevier
Objective To evaluate the incidence of direct admission of infants with Down syndrome to
the postnatal ward (well newborn nursery) vs the neonatal intensive care unit (NICU), and to …

Improved survival in Down syndrome over the last 60 years and the impact of perinatal factors in recent decades

EJ Glasson, A Jacques, K Wong, J Bourke… - The Journal of …, 2016 - Elsevier
Objective To calculate the survival of people with Down syndrome over the past 60 years
and the influence of major perinatal factors by using linked population-based data. Study …