Circadian rhythms are daily oscillations in various biological processes, generated by the
feedback loops of eight core circadian genes: Period1 (Per1), Period2 (Per2), Period3 …

Circadian rhythms are fundamental biological systems in most organisms. Epidemiological
and animal studies have demonstrated that disruption of circadian rhythms is linked to tumor …

The circadian timing system controls about 40% of the transcriptome and is important in the
regulation of a wide variety of biological processes including metabolic and proliferative …

Circadian rhythm plays an important role in the regulation of digestive system. The human
circadian rhythm is controlled by at least nine circadian genes. The aims of this study are to …

Disruption of circadian machinery appears to be associated with the acceleration of tumor
development. To evaluate the function of the circadian clock during neoplastic …

There is a growing body of evidence that disturbed circadian clock gene expression is
associated with tumor development and tumor progression. Based on our initial experiments …

Circadian clock genes regulate 10–15% of the transcriptome, and might function as tumor
suppressor genes. Relatively little is known about the circadian clock in tumors and its effect …

Background Recent studies have shown that disruption of circadian rhythms is one of the
tumor promoting factors which contribute to mammalian cancer development and …

The circadian rhythm is generated at the cellular level by a molecular clock system that
involves specific genes. Studies have revealed that circadian clock disruption is a control …

The clock gene machinery controls cellular metabolism, proliferation, and key functions,
such as DNA damage recognition and repair. Dysfunction of the circadian clock is involved …