Lessons from surface-initiated polymerization are applied to grow cell-penetrating poly
(disulfide) s directly on substrates of free choice. Reductive depolymerization after cellular …

Substrate-initiated, self-inactivating, cell-penetrating poly (disulfide) s (siCPDs) are
introduced as general transporters for the covalent delivery of unmodified substrates of free …

The delivery of therapeutic agents into target cells is a challenging task. Cell penetration and
intracellular targeting were recently addressed with biodegradable cell-penetrating poly …

Protein delivery with cell-penetrating poly(disulfide)s - Chemical Communications (RSC
Publishing) DOI:10.1039/C5CC07460F Royal Society of Chemistry View PDF VersionPrevious …

We report that the depolymerization kinetics of cell-penetrating poly (disulfide) s depend
exclusively on their length and propose a kinetic uptake model to explain why their …

The efficient delivery of bioactive compounds into cells is a major challenge in drug
discovery. We report herein the development of novel methods for intracellular delivery of …

Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …

Grafting-from (GF) is an important yet underdeveloped strategy toward protein–polymer
conjugates. Here, we report a simple cryopolymerization method that enables highly efficient …

Poly (disulfide) s are an emerging class of sulfur-containing polymers with applications in
medicine, energy, and functional materials. However, the constituent dynamic covalent S–S …

A strategy is reported for controlling the architecture of poly (disulfide) s by ring-opening
polymerization. Aryl thiol initiators shift the ring–chain equilibrium to yield cyclic polymers …