Serotonin augmentation reduces response to attack in aggressive individuals

ME Berman, MS McCloskey, JR Fanning… - Psychological …, 2009 - journals.sagepub.com
We tested the theory that central serotonin (5-hydroxytryptamine, or 5-HT) activity regulates
aggression by modulating response to provocation. Eighty men and women (40 with and 40 …

The serotonin hypothesis of aggression revisited

ME Berman, JI Tracy, EF Coccaro - Clinical psychology review, 1997 - Elsevier
Many contemporary theorists believe serotonin (5-HT) neurotransmitter functioning plays a
role in the regulation of human aggressive behavior. We argue that the evidence supporting …

Serotonin and aggression

B Olivier - Annals of the New York Academy of Sciences, 2004 - Wiley Online Library
The neurotransmitter serotonin (5‐HT) has been implicated in the modulation of aggression
in animals and humans. A longstanding dogma that aggression and serotonergic activity are …

Serotonin receptor sensitivity and aggression

S Wetzler, RS Kahn, GM Asnis, M Korn… - Psychiatry …, 1991 - Elsevier
This study investigated the relationship between increased serotonin (5-hydroxytryptamine,
5HT) receptor sensitivity and human aggression. A low oral dose of meta …

Modulatory action of serotonin in aggressive behaviour

B Olivier, J Mos, M Tulp, J Schipper… - … pharmacology of 5-HT, 2013 - taylorfrancis.com
Serotonin (5–HT) has been suggested to play an important role in the control of aggressive
behaviour in animals (Valzelli, 1981) and man (Muhlbauer, 1985). This does not imply …

Effects of acute alcohol intoxication and paroxetine on aggression in men

MS McCloskey, ME Berman… - Alcoholism: Clinical …, 2009 - Wiley Online Library
Background: The purpose of this study was to examine the role of the serotonin (5‐HT)
system in alcohol‐related aggression. Methods: Specifically, we experimentally examined …

Acute effect of altered tryptophan levels and alcohol on aggression in normal human males

RO Pihl, SN Young, P Harden, S Plotnick… - …, 1995 - Springer
Normal males received amino acid mixtures designed to raise or lower tryptophan
availability, and thus to raise or lower brain serotonin synthesis. They also received …

Violence and serotonin: influence of impulse control, affect regulation, and social functioning

M Krakowski - The Journal of neuropsychiatry and clinical …, 2003 - Am Neuropsych Assoc
There has been much interest in the role of serotonin in aggressive behavior during the past
two decades, but no simple one-to-one causal relationship has been found between this …

Elevation and reduction of plasma tryptophan and their effects on aggression and perceptual sensitivity in normal males

SE Smith, RO Pihl, SN Young, FR Ervin - Aggressive Behavior, 1986 - Wiley Online Library
Data from experimental animals suggest that 5‐hydroxytryptamine (5HT) may have an
inhibitory effect on aggression, while clinical studies have found a correlation between …

Influence of trait hostility on tryptophan depletion-induced laboratory aggression

DM Dougherty, JM Bjork, DM Marsh, FG Moeller - Psychiatry Research, 1999 - Elsevier
Previous research has indicated that laboratory aggression in men increases after
temporarily reducing the synthesis and neurotransmission of serotonin (5-HT) in the brain …