Genetic and epigenetic etiology of inflammatory bowel disease: An update

S Jarmakiewicz-Czaja, M Zielińska, A Sokal, R Filip - Genes, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and
remission of the disease. The etiology of IBD is not fully understood. Many studies point to …

Inflammatory bowel disease and genetics

RK Weersma, HM Van Dullemen… - Alimentary …, 2007 - Wiley Online Library
Introduction Inflammatory bowel disease (IBD) comprising ulcerative colitis (UC) and
Crohn's disease (CD) is multigenic disorder. Tremendous progress has been achieved in …

Inflammatory bowel disease: review from the aspect of genetics

S Ishihara, MM Aziz, T Yuki, H Kazumori… - Journal of …, 2009 - Springer
Regardless of how inflammatory bowel disease (IBD) is defined, the term “genetic
susceptibility” is always included. Due to substantial progress in the characterization of …

[HTML][HTML] Inflammatory bowel disease: pathogenesis

YZ Zhang, YY Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is
characterized by chronic relapsing intestinal inflammation. It has been a worldwide health …

[HTML][HTML] Inflammatory bowel disease: genetics, epigenetics, and pathogenesis

I Loddo, C Romano - Frontiers in immunology, 2015 - frontiersin.org
Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …

Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility

BD Ye, DPB McGovern - Expert review of clinical immunology, 2016 - Taylor & Francis
Epidemiological and clinical studies have suggested that the pathogenesis of inflammatory
bowel disease (IBD) is strongly influenced by genetic predisposition. Beyond the limitations …

Genetics and epigenetics of IBD

V Annese - Pharmacological research, 2020 - Elsevier
Inflammatory bowel diseases (IBD) are chronic intermittent inflammatory disorders of the
gastrointestinal tract of unknown etiology but a clear genetic predisposition. Prompted by the …

The genetic architecture of inflammatory bowel disease: past, present and future

I Cleynen, S Vermeire - Current opinion in gastroenterology, 2015 - journals.lww.com
Genetic, transcriptomic and epigenetic studies have offered exciting clues about IBD
pathogenesis but are unlikely to provide all answers. To fully grasp the function of disease …

Clinical relevance of advances in genetics and pharmacogenetics of IBD

T Ahmad, CP Tamboli, D Jewell, JF Colombel - Gastroenterology, 2004 - Elsevier
Crohn's disease and ulcerative colitis result from an inappropriate response of the mucosal
immune system to the normal enteric flora in a genetically susceptible individual. During the …

Clinical implications of inflammatory bowel disease genetics on phenotype

FJR Cummings, DP Jewell - Inflammatory bowel diseases, 2005 - academic.oup.com
The genetic revolution has been with us for over a decade now. We have yet to see this
impacting the care of patients except in a few rare examples. However, progress has been …