Retrotransposable elements (RTEs) have actively multiplied over the past 80 million years of
primate evolution, and as a consequence, such elements collectively occupy∼ 40% of the …

Long interspersed element-1 (LINE-1 or L1) is a repetitive DNA retrotransposon capable of
duplication by a copy-and-paste genetic mechanism. Scattered throughout mammalian …

Half the human genome is made of transposable elements (TEs), whose ongoing activity
continues to impact our genome. LINE-1 (or L1) is an autonomous non-LTR retrotransposon …

Neural progenitor cells undergo somatic retrotransposition events, mainly involving L1
elements, which can be potentially deleterious. Here, we analyze the whole genomes of 20 …

Long interspersed element-1 (L1) retrotransposons compose∼ 20% of the mammalian
genome, and ongoing L1 retrotransposition events can impact genetic diversity by various …

Retrotransposons are transposable elements (TEs) capable of “jumping” in germ, embryonic
and tumor cells and, as is now clearly established, in the neuronal lineage. Mosaic TE …

Over the past decade, major discoveries in retrotransposon biology have depicted the
neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 …

Long interspersed element 1 (LINE-1 or L1) retrotransposons have generated one-third of
the human genome, and their ongoing mobility is a source of inter-and intraindividual …

ABSTRACT Long interspersed element‐1 (LINE‐1 or L1) is a transposable element with the
ability to self‐mobilize throughout the human genome. The L1 elements found in the human …

The genetic mechanisms underlying the expansion in size and complexity of the human
brain remain poorly understood. Long interspersed nuclear element–1 (L1) …