“Switch I” mutant forms of the bacterial enhancer-binding protein NtrC that perturb the response to DNA
D Yan, S Kustu - Proceedings of the National Academy of …, 1999 - National Acad Sciences
NtrC (nitrogen regulatory protein C) is a bacterial enhancer-binding protein of 469 residues
that activates transcription by σ54-holoenzyme. A region of its transcriptional activation …
that activates transcription by σ54-holoenzyme. A region of its transcriptional activation …
Repressor forms of the enhancer-binding protein NtrC: some fail in coupling ATP hydrolysis to open complex formation by σ54-holoenzyme
AK North, DS Weiss, H Suzuki, Y Flashner… - Journal of molecular …, 1996 - Elsevier
NtrC (nitrogen regulatory protein C) is a bacterial enhancer-binding protein that activates
transcription by catalyzing isomerization of closed complexes between σ54-holoenzyme and …
transcription by catalyzing isomerization of closed complexes between σ54-holoenzyme and …
Constitutive forms of the enhancer-binding protein NtrC: evidence that essential oligomerization determinants lie in the central activation domain
Y Flashner, DS Weiss, J Keener, S Kustu - Journal of molecular biology, 1995 - Elsevier
Nitrogen regulatory protein C (NtrC) is a bacterial enhancer-binding protein that activates
transcription by the σ54-holoenzyme. To activate transcription, NtrC must hydrolyze ATP, a …
transcription by the σ54-holoenzyme. To activate transcription, NtrC must hydrolyze ATP, a …
Physical evidence for a phosphorylation-dependent conformational change in the enhancer-binding protein NtrC
The bacterial enhancer-binding protein nitrogen regulatory protein C (NtrC) activates
transcription by σ54-containing RNA polymerase in a reaction that depends on ATP …
transcription by σ54-containing RNA polymerase in a reaction that depends on ATP …
The bacterial enhancer-binding protein NTRC is a molecular machine: ATP hydrolysis is coupled to transcriptional activation.
A Wedel, S Kustu - Genes & development, 1995 - genesdev.cshlp.org
NTRC is a prokaryotic enhancer-binding protein that activates transcription by sigma 54-
holoenzyme. NTRC has an ATPase activity that is required for transcriptional activation …
holoenzyme. NTRC has an ATPase activity that is required for transcriptional activation …
The major dimerization determinants of the nitrogen regulatory protein NTRC from enteric bacteria lie in its carboxy-terminal domain
KE Klose, AK North, KM Stedman, S Kustu - Journal of molecular biology, 1994 - Elsevier
The NTRC protein (nitrogen regulatory protein C) of enteric bacteria is an enhancer-binding
protein that activates transcription by the σ 54-holoenzyme form of RNA polymerase. NTRC …
protein that activates transcription by the σ 54-holoenzyme form of RNA polymerase. NTRC …
The prokaryotic enhancer binding protein NTRC has an ATPase activity which is phosphorylation and DNA dependent.
S Austin, R Dixon - The EMBO journal, 1992 - embopress.org
The prokaryotic activator protein NTRC binds to enhancer‐like elements and activates
transcription in response to nitrogen limitation by catalysing open complex formation by …
transcription in response to nitrogen limitation by catalysing open complex formation by …
Unusual oligomerization required for activity of NtrC, a bacterial enhancer-binding protein
C Wyman, I Rombel, AK North, C Bustamante, S Kustu - Science, 1997 - science.org
Nitrogen regulatory protein C (NtrC) contacts a bacterial RNA polymerase from distant
enhancers by means of DNA loops and activates transcription by allowing polymerase to …
enhancers by means of DNA loops and activates transcription by allowing polymerase to …
Glutamate at the site of phosphorylation of nitrogen-regulatory protein NTRC mimics aspartyl-phosphate and activates the protein
The NTRC protein of enteric bacteria is an enhancer-binding protein that activates
transcription by the σ 54-holoenzyme form of RNA polymerase under nitrogen-limiting …
transcription by the σ 54-holoenzyme form of RNA polymerase under nitrogen-limiting …
Mechanism of transcriptional activation by NtrC
SC Porter, AK North, S Kustu - Two‐Component Signal …, 1995 - Wiley Online Library
In the case of nitrogen regulatory protein C (NtrC), both nucleotide hydrolysis and
transcriptional activation depend on phosphorylation of an aspartate residue in the N …
transcriptional activation depend on phosphorylation of an aspartate residue in the N …
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