[HTML][HTML] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

C Motozono, M Toyoda, J Zahradnik, A Saito… - Cell host & …, 2021 - cell.com
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …

The variation of SARS-CoV-2 and advanced research on current vaccines

Y Jiang, Q Wu, P Song, C You - Frontiers in Medicine, 2022 - frontiersin.org
Over the past 2 years, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
caused the coronavirus disease 2019 (COVID-19) and rapidly spread worldwide. In the …

[HTML][HTML] SARS-CoV-2 501Y. V2 variants lack higher infectivity but do have immune escape

Q Li, J Nie, J Wu, L Zhang, R Ding, H Wang, Y Zhang… - Cell, 2021 - cell.com
The 501Y. V2 variants of SARS-CoV-2 containing multiple mutations in spike are now
dominant in South Africa and are rapidly spreading to other countries. Here, experiments …

The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies

S Zhang, L Wang, G Cheng - Molecular therapy, 2022 - cell.com
The SARS-CoV-2 virus, the pathogen causing COVID-19, has caused more than 200 million
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …

Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization

L Zhang, Z Cui, Q Li, B Wang, Y Yu, J Wu, J Nie… - Communications …, 2021 - nature.com
Emerging mutations in SARS-CoV-2 cause several waves of COVID-19 pandemic. Here we
investigate the infectivity and antigenicity of ten emerging SARS-CoV-2 variants—B. 1.1 …

Less neutralization evasion of SARS-CoV-2 BA. 2.86 than XBB sublineages and CH. 1.1

Y Hu, J Zou, C Kurhade, X Deng… - Emerging microbes & …, 2023 - Taylor & Francis
ABSTRACT The highly mutated BA. 2.86, with over 30 spike protein mutations in
comparison to Omicron BA. 2 and XBB. 1.5 variants, has raised concerns about its potential …

Repurposing drugs, ongoing vaccine, and new therapeutic development initiatives against COVID-19

RP Saha, AR Sharma, MK Singh, S Samanta… - Frontiers in …, 2020 - frontiersin.org
As the COVID-19 is still growing throughout the globe, a thorough investigation into the
specific immunopathology of SARS-CoV-2, its interaction with the host immune system and …

The outbreak of SARS‐CoV‐2 Omicron lineages, immune escape, and vaccine effectivity

Y Zhou, H Zhi, Y Teng - Journal of medical virology, 2023 - Wiley Online Library
As of November 2021, several SARS‐CoV‐2 variants appeared and became dominant
epidemic strains in many countries, including five variants of concern (VOCs) Alpha, Beta …

SARS-CoV-2 lambda variant remains susceptible to neutralization by mRNA vaccine-elicited antibodies and convalescent serum

T Tada, H Zhou, BM Dcosta, MI Samanovic… - BioRxiv, 2021 - biorxiv.org
The SARS-CoV-2 lambda variant (lineage C. 37) was designated by the World Health
Organization as a variant of interest and is currently increasing in prevalence in South …

Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost

J Ai, H Zhang, Y Zhang, K Lin, Y Zhang… - Emerging microbes & …, 2022 - Taylor & Francis
The emerging new VOC B. 1.1. 529 (Omicron) variant has raised serious concerns due to
multiple mutations, reported significant immune escape, and unprecedented rapid …