Recently, apelin was characterised as a novel adipose-expressed factor which is
upregulated in rodent and human obesity and influences cardiovascular function, as well as …

The results presented herein demonstrate that apelin is expressed and secreted by both
human and mouse adipocytes. Apelin mRNA levels in isolated adipocytes are close to other …

We have recently identified apelin as a novel adipokine up‐regulated by insulin and obesity.
Since obesity and insulin resistance are associated with chronically elevated levels of both …

This paper focuses on the contribution of apelin in obesity associated regulations/
dysregulations. The conclusions are summarized as follows:(i) apelin is produced by fat …

The novel 36-amino acid peptide, apelin, is the endogenous ligand for the orphan receptor
APJ. Apelin may play important roles in the regulation of the cardiovascular system and the …

Apelin is a peptide present in different cell types and secreted by adipocytes in humans and
rodents. Apelin exerts its effects through a G-protein-coupled receptor called APJ. During the …

Objective: Apelin is an adipokine which plays a role in the regulation of glucose
homeostasis and may contribute to the link between increased adipose tissue mass and …

Apelin is a peptide known as the ligand of the G-protein-coupled receptor APJ. Several
active apelin forms exist such as apelin-36, apelin-17, apelin-13, and the pyroglutamated …

Apelin, an adipocyte-secreted factor upregulated by insulin, is increased in adipose tissue
(AT) and plasma with obesity. Apelin was recently identified as a new player in the control of …

Lipoic acid (LA) is an antioxidant with therapeutic properties on several diseases like
diabetes and obesity. Apelin is a novel adipokine with potential beneficial actions on …