Background: DNA methylation is implicated in coronary heart disease (CHD), but current
evidence is based on small, cross-sectional studies. We examined blood DNA methylation …

Importance American Indian communities experience a high burden of coronary heart
disease (CHD). Strategies are needed to identify individuals at risk and implement …

Epidemiological studies have demonstrated that genetic, environmental, behavioral, and
clinical factors contribute to cardiovascular disease development. How these risk factors …

Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …

Background DNA methylation profiles are responsive to environmental stimuli and metabolic
shifts. This makes DNA methylation a potential biomarker of environmental-related and …

Rationale: Acute coronary syndrome (ACS) is a leading cause of death worldwide. Immune
functions play a vital role in ACS development; however, whether epigenetic modulation …

Coronary heart disease (CHD) is a type of cardiovascular disease (CVD) that affects the
coronary arteries, which provide oxygenated blood to the heart. It is a major cause of …

Background: Epigenetic features such as DNA hypomethylation have been associated with
conditions related to cardiovascular risk. We evaluated whether lower blood DNA …

Background and aims The aim of this study was to perform a systematic review of the
association between DNA methylation and coronary heart disease (CHD) or related …

Background: Cardiovascular health (CVH) from young adulthood is strongly associated with
an individual's future risk of cardiovascular disease (CVD) and total mortality. Defining …