Recent studies have shown that persistent SARS-CoV-2 infections in immunocompromised
patients can trigger the accumulation of an unusual high number of mutations with potential …

SARS-CoV-2 causes a spectrum of COVID-19 disease, the immunological basis of which
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …

Mathematical models of infectious diseases exhibit robust dynamics, such as stable
endemic, disease-free equilibriums or convergence of the solutions to periodic epidemic …

Background The development and widespread use of an effective SARS-CoV-2 vaccine
could prevent substantial morbidity and mortality associated with COVID-19 and mitigate the …

Background The COVID-19 outbreak has become the worst pandemic in at least a century.
To fight this disease, a global effort led to the development of several vaccines at an …

Background Comorbidities are risk factors for development of severe coronavirus disease
2019 (COVID-19). However, the extent to which an underlying comorbidity influences the …

It is highly desired to explore the interventions of COVID-19 for early treatment strategies.
Such interventions are still under consideration. A model is benchmarked research and …

The identification of SARS-CoV-2-specific T cell receptor (TCR) sequences is critical for
understanding T cell responses to SARS-CoV-2. Accordingly, we reanalyze publicly …

Little is known about the time-dependent immune responses in severe COVID-19. Data of
15 consecutive patients were sequentially recorded from intensive care unit admission …

Sparse data exist on the complex natural immunity to SARS-CoV-2 at the population level.
We applied a well-validated multiplex serology test in 5000 participants of a general …