Long non-coding RNA regulation of epithelial–mesenchymal transition in cancer metastasis

Q Xu, F Deng, Y Qin, Z Zhao, Z Wu, Z Xing, A Ji… - Cell death & …, 2016 - nature.com
Metastasis is a multistep process starting with the dissemination of tumor cells from a
primary site and ending with secondary tumor development in an anatomically distant …

Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications

H Khanbabaei, S Ebrahimi… - Journal of Experimental …, 2022 - Springer
Epithelial-mesenchymal transition (EMT) is a fundamental process for embryonic
development during which epithelial cells acquire mesenchymal characteristics, and the …

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis

S Dhamija, S Diederichs - International journal of cancer, 2016 - Wiley Online Library
Metastasis is a multistep process that involves the dissemination of cells from the primary
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …

Tumor microenvironment and noncoding RNAs as co‐drivers of epithelial–mesenchymal transition and cancer metastasis

K Drak Alsibai, D Meseure - Developmental Dynamics, 2018 - Wiley Online Library
Reciprocal interactions between cancer cells and tumor microenvironment (TME) are crucial
events in tumor progression and metastasis. Pervasive stromal reprogramming of TME …

Long noncoding RNAs in cancer metastasis

SJ Liu, HX Dang, DA Lim, FY Feng… - Nature Reviews Cancer, 2021 - nature.com
Metastasis is a major contributor to cancer-associated deaths. It is characterized by a
multistep process that occurs through the acquisition of molecular and phenotypic changes …

Long non-coding RNAs: key regulators of epithelial-mesenchymal transition, tumour drug resistance and cancer stem cells

R Heery, SP Finn, S Cuffe, SG Gray - Cancers, 2017 - mdpi.com
Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …

Long non-coding RNAs modulate tumor microenvironment to promote metastasis: novel avenue for therapeutic intervention

SK Baba, SK Baba, R Mir, I Elfaki… - Frontiers in cell and …, 2023 - frontiersin.org
Cancer is a devastating disease and the primary cause of morbidity and mortality worldwide,
with cancer metastasis responsible for 90% of cancer-related deaths. Cancer metastasis is a …

Long noncoding RNA and epithelial mesenchymal transition in cancer

M Gugnoni, A Ciarrocchi - International journal of molecular sciences, 2019 - mdpi.com
Epithelial–mesenchymal transition (EMT) is a multistep process that allows epithelial cells to
acquire mesenchymal properties. Fundamental in the early stages of embryonic …

Long non-coding RNAs and cancer metastasis: Molecular basis and therapeutic implications

H Ming, B Li, L Zhou, A Goel, C Huang - Biochimica et Biophysica Acta …, 2021 - Elsevier
Cancer metastasis, defined by the epithelial to mesenchymal transition (EMT) of tumor cells,
disseminates from the primary site to progressively colonize in distant tissues, and accounts …

lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions

EM McCabe, TP Rasmussen - Seminars in cancer biology, 2021 - Elsevier
Epithelial to mesenchymal transition (EMT) is a cellular process in which cells composing
epithelial tissue lose requirements for physical contact with neighboring cells and acquire …