Repurposing of drugs targeting the cytokine storm induced by SARS‐CoV‐2

WH Ng, PCH Tang, S Mahalingam… - British Journal of …, 2023 - Wiley Online Library
A cytokine storm is one of the leading causes of acute respiratory distress syndrome (ARDS)
and sepsis‐associated multiple organ failure in many respiratory viral infections, including …

Safety of drugs used during the first wave of COVID-19: A hospital-registry-based study

C Aguilera, I Danés, E Guillén, A Vimes, M Bosch… - Diagnostics, 2022 - mdpi.com
The emergency of the coronavirus disease 2019 (COVID-19) pandemic led to the off-label
use of drugs without data on their toxicity profiles in patients with COVID-19, or on their …

COVID19 alert Do we know our enemy?

K Antoniou, M Bolaki, E Bibaki, E Vasarmidi… - …, 2020 - search.ebscohost.com
Abstract SARS-coronavirus 2 (SARS-CoV-2), the etiologic agent of the new lung disease
COVID-19 is closely related to SARS-CoV, and together with MERS-CoV are three new …

A scoping review of pharmacological management of postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection in 2021

E Carson, AN Hemenway - American Journal of Therapeutics, 2022 - journals.lww.com
Background: Postacute sequelae of severe acute respiratory syndrome coronavirus 2
infection (PASC), or long-COVID, are signs and symptoms that persist after the acute phase …

[HTML][HTML] A narrative review of non-pharmacological management of SARS-CoV-2 respiratory failure: a call for an evidence based approach

R Vashisht, S Krishnan, A Duggal - Annals of Translational …, 2020 - ncbi.nlm.nih.gov
A novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) belonging to genus
beta-coronavirus has been associated with an acute respiratory disease termed coronavirus …

Diagnosis and management of acute respiratory distress syndrome in a time of COVID-19

S Kassirian, R Taneja, S Mehta - Diagnostics, 2020 - mdpi.com
Acute respiratory distress syndrome (ARDS) remains a serious illness with significant
morbidity and mortality, characterized by hypoxemic respiratory failure most commonly due …

2021 acute respiratory distress syndrome update, with coronavirus disease 2019 focus

C Welker, J Huang, IJN Gil, H Ramakrishna - Journal of Cardiothoracic and …, 2022 - Elsevier
Acute respiratory distress syndrome (ARDS) is a heterogeneous lung disease responsible
for significant morbidity and mortality among critically ill patients, including those infected …

Evaluation of interleukin‐1 and interleukin‐6 receptor antagonists in a murine model of acute lung injury

É Meunier, M Aubin vega, D Adam… - Experimental …, 2024 - Wiley Online Library
The acute exudative phase of acute respiratory distress syndrome (ARDS), a severe form of
respiratory failure, is characterized by alveolar damage, pulmonary oedema, and an …

Pulmonary inflammatory response in lethal COVID-19 reveals potential therapeutic targets and drugs in phases III/IV clinical trials

A López-Cortés, S Guerrero, E Ortiz-Prado… - Frontiers in …, 2022 - frontiersin.org
Background: It is imperative to identify drugs that allow treating symptoms of severe COVID-
19. Respiratory failure is the main cause of death in severe COVID-19 patients, and the host …

[HTML][HTML] Reducing the fatality rate of COVID-19 by applying clinical insights from immuno-oncology and lung transplantation

FM Uckun - Frontiers in pharmacology, 2020 - frontiersin.org
There is an urgent need to identify effective strategies that can stop or reverse the
inflammatory process that causes acute lung injury, ARDS, and multi-organ failure in COVID …