The development and function of our brain are governed by a genetic blueprint, which
reflects dynamic changes over the history of evolution. Recent progress in genetics and …

Our understanding of the evolution, formation, and pathological disruption of human brain
circuits is impeded by a lack of comprehensive data on the developing brain transcriptome …

The cerebral cortex is the source of our most complex cognitive capabilities and a
vulnerable target of many neurological and neuropsychiatric disorders. Transcriptomics …

The evolution of the human brain has resulted in numerous specialized features including
higher cognitive processes such as language. Knowledge of whole-genome sequence and …

The brain, our most complex organ, is at the root of both the cognitive and behavioral
repertoires that make us unique as a species and underlies susceptibility to neuropsychiatric …

Human evolution is characterized by a rapid increase in brain size and complexity. Decades
of research have made important strides in identifying anatomical and physiological …

INTRODUCTION Improved understanding of how the developing human nervous system
differs from that of closely related nonhuman primates is fundamental for teasing out human …

One of the biggest challenges in neuroscience is illuminating the architecture of
developmental brain disorders, which include structural malformations of the brain and …

Understanding human-specific patterns of brain gene expression and regulation can
provide key insights into human brain evolution and speciation. Here, we use next …

Developmental changes in the temporal and spatial regulation of gene expression drive the
emergence of normal mature brain function, while disruptions in these processes underlie …