Objective: Integrin-associated protein (CD47) binds specifically to the inhibitory receptor
signal-regulatory protein. This study was designed to evaluate the role of CD47 in natural …

Elevated CD47 expression in some cancers is associated with decreased survival and
limited clearance by phagocytes expressing the CD47 counterreceptor SIRPα. In contrast …

Head and neck squamous cell carcinoma (HNSCC) is considered as an
immunosuppressive disease, with impaired tumor-infiltrating T lymphocytes and increased …

The relationship between the immune system and cancer growth and aggravation has been
discussed over a century. A number of molecules have been shown to participate in this …

CD47 is a membrane receptor that belongs to the immunoglobulin superfamily and plays an
important role in the mechanisms of tumor immune escape. CD47 participates in tumor …

Tumor-associated macrophages (TAM) have been classified into an immunostimulatory M1
subset against microbes and malignancies, and an immunoregulatory M2 subset that …

CD47 is a versatile cell‐surface molecule expressed on nearly all haematopoietic cells. In its
capacity as a thrombospondin‐1 (TSP‐1) receptor, CD47 has recently been shown to …

Abstract Integrin-associated protein (CD47) is ubiquitously expressed on the surface of cells
and functions as an identifier of self. In blood cancer, tumor cells expressing CD47 evade …

CD47, a “don't eat me” signal for phagocytic cells, is expressed on the surface of all human
solid tumor cells. Analysis of patient tumor and matched adjacent normal (nontumor) tissue …

The treatment of breast cancer largely depends on the utilization of immunogenic
chemotherapeutics, which, as a common leitmotif, stimulate the exposure of calreticulin …