Dexamethasone: Therapeutic potential, risks, and future projection during COVID-19 pandemic

S Noreen, I Maqbool, A Madni - European journal of pharmacology, 2021 - Elsevier
The current outbreak of novel COVID-19 challenges the development of an efficient
treatment plan as soon as possible. Several promising treatment options stand out as …

Potential adverse effects of dexamethasone therapy on COVID-19 patients: review and recommendations

F Chen, L Hao, S Zhu, X Yang, W Shi, K Zheng… - Infectious diseases and …, 2021 - Springer
In the context of the coronavirus disease 2019 (COVID-19) pandemic, the global healthcare
community has raced to find effective therapeutic agents against severe acute respiratory …

Dexamethasone for the treatment of coronavirus disease (COVID-19): a review

MH Ahmed, A Hassan - SN comprehensive clinical medicine, 2020 - Springer
Abstract The World Health Organization (WHO) declared COVID-19 (novel coronavirus) as a
global pandemic in the middle of March 2020, after the disease spread to more than 150 …

Comparing efficacy and safety of different doses of dexamethasone in the treatment of COVID-19: a three-arm randomized clinical trial

N Toroghi, L Abbasian, A Nourian… - Pharmacological …, 2022 - Springer
Background and objectives Corticosteroids are commonly used in the treatment of
hospitalized patients with COVID-19. The goals of the present study were to compare the …

Role of dexamethasone and methylprednisolone corticosteroids in coronavirus disease 2019 hospitalized patients: a review

J Mehta, R Rolta, BB Mehta, N Kaushik… - Frontiers in …, 2022 - frontiersin.org
The WHO announced coronavirus disease 2019 (COVID-19) as a pandemic disease
globally on March 11, 2020, after it emerged in China. The emergence of COVID-19 has …

Efficacy of dexamethasone treatment for patients with the acute respiratory distress syndrome caused by COVID-19: study protocol for a randomized controlled …

J Villar, JM Añón, C Ferrando, G Aguilar, T Muñoz… - Trials, 2020 - Springer
Background There are no specific generally accepted therapies for the coronavirus disease
2019 (COVID-19). The full spectrum of COVID-19 ranges from asymptomatic disease to mild …

No clinical benefit of high dose corticosteroid administration in patients with COVID-19: a preliminary report of a randomized clinical trial

H Jamaati, SMR Hashemian, B Farzanegan… - European journal of …, 2021 - Elsevier
The aim of this study was to evaluate the clinical effects of dexamethasone administration in
patients with mild to moderate acute respiratory distress syndrome (ARDS) due to …

[PDF][PDF] Dexamethasone for COVID-19? Not so fast

TC Theoharides, P Conti - J Biol Regul Homeost Agents, 2020 - researchgate.net
Recent announcements indicated, without sharing any distinct published set of results, that
use of the corticosteroid dexamethasone in a large trial in the UK apparently reduced …

Dexamethasone in hospitalized patients with Covid-19

RECOVERY Collaborative Group - New England Journal of …, 2021 - Mass Medical Soc
Abstract Background Coronavirus disease 2019 (Covid-19) is associated with diffuse lung
damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby …

Dexamethasone for severe COVID-19: how does it work at cellular and molecular levels?

T Kino, I Burd, JH Segars - International journal of molecular sciences, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) caused by infection of the severe respiratory
syndrome coronavirus-2 (SARS-CoV-2) significantly impacted human society. Recently, the …