[HTML][HTML] Single-cell sequencing of peripheral mononuclear cells reveals distinct immune response landscapes of COVID-19 and influenza patients
Summary The coronavirus disease 2019 (COVID-19) pandemic poses a current world-wide
public health threat. However, little is known about its hallmarks compared to other infectious …
public health threat. However, little is known about its hallmarks compared to other infectious …
Identification of IL-6 signalling components as predictors of severity and outcome in COVID-19
MÁ Rodríguez-Hernández, D Carneros… - Frontiers in …, 2022 - frontiersin.org
IL-6 is one of the major mediators of the hyper-inflammatory responses with complex
biological functions as it can signal via different modes of action. IL-6 by classical signalling …
biological functions as it can signal via different modes of action. IL-6 by classical signalling …
IL-33 in COVID-19: friend or foe?
The COVID-19 pandemic, caused by the highly transmissible and pathogenic severe acute
respiratory syndrome coronavirus 2 (SAR-CoV-2), has led to more than 2.7 million deaths …
respiratory syndrome coronavirus 2 (SAR-CoV-2), has led to more than 2.7 million deaths …
Increased IL‐10‐producing regulatory T cells are characteristic of severe cases of COVID‐19
J Neumann, T Prezzemolo… - Clinical & …, 2020 - Wiley Online Library
Objectives The pandemic spread of the coronavirus SARS‐CoV‐2 is due, in part, to the
immunological properties of the host–virus interaction. The clinical presentation varies from …
immunological properties of the host–virus interaction. The clinical presentation varies from …
Novel coronavirus disease 2019 (COVID-19) and cytokine storms for more effective treatments from an inflammatory pathophysiology
S Yokota, T Miyamae, Y Kuroiwa… - Journal of Clinical …, 2021 - mdpi.com
The Novel Coronavirus Disease 2019 (COVID-19) has swept the world and caused a global
pandemic. SARS-CoV-2 seems to have originated from bats as their reservoir hosts over …
pandemic. SARS-CoV-2 seems to have originated from bats as their reservoir hosts over …
COVID-19 and the role of cytokines in this disease
A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
COVID-19: in the eye of the cytokine storm
R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …
Clonal expansion and activation of tissue-resident memory-like TH17 cells expressing GM-CSF in the lungs of patients with severe COVID-19
Hyperinflammation contributes to lung injury and subsequent acute respiratory distress
syndrome with high mortality in patients with severe coronavirus disease 2019 (COVID-19) …
syndrome with high mortality in patients with severe coronavirus disease 2019 (COVID-19) …
Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …
AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …
Heightened circulating interferon-inducible chemokines, and activated pro-cytolytic Th1-cell phenotype features covid-19 aggravation in the second week of illness
C Tincati, ES Cannizzo, M Giacomelli… - Frontiers in …, 2020 - frontiersin.org
Covid-19 features a delayed onset of critical illness occurring approximately one week from
the beginning of symptoms, which corresponds to the bridging of innate and adaptive …
the beginning of symptoms, which corresponds to the bridging of innate and adaptive …