Randomized clinical trial to evaluate a routine full anticoagulation strategy in patients with coronavirus infection (SARS-CoV2) admitted to hospital: rationale and …

RD Lopes, RHM Furtado, AVS Macedo… - American heart …, 2021 - Elsevier
Background Observational studies have suggested a higher risk of thrombotic events in
patients with coronavirus disease 2019 (COVID-19). Moreover, elevated D-dimer levels …

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label …

RD Lopes, RHM Furtado, AVS Macedo, B Bronhara… - The Lancet, 2021 - thelancet.com
Background COVID-19 is associated with a prothrombotic state leading to adverse clinical
outcomes. Whether therapeutic anticoagulation improves outcomes in patients hospitalised …

Anticoagulation and bleeding risk in patients with COVID-19

N Musoke, KB Lo, J Albano, E Peterson, R Bhargav… - Thrombosis research, 2020 - Elsevier
Background There is no current standardized approach to anticoagulation in patients with
Coronavirus Disease 2019 (COVID-19) while potential bleeding risks remain. Our study …

Use of anticoagulants in COVID-19: a review

S Ngu, JK Smith, M Goldin - American Journal of Therapeutics, 2022 - journals.lww.com
Background: Coronavirus disease 2019 (COVID-19) is associated with elevated rates of
major and fatal thrombotic events, postulated to be the result of a hypercoagulable state …

Intensity of anticoagulation and survival in patients hospitalized with COVID-19 pneumonia

A Hsu, Y Liu, AS Zayac, AJ Olszewski, JL Reagan - Thrombosis research, 2020 - Elsevier
Background SARS-CoV-2 infection has noted derangements in coagulation markers along
with significant thrombotic complications. Post-mortem examinations show severe …

Anticoagulant Treatment Regimens in Patients With Covid‐19: A Meta‐Analysis

A Jorda, JM Siller‐Matula, M Zeitlinger… - Clinical …, 2022 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is associated with a hypercoagulable state. It has
been hypothesized that higher‐dose anticoagulation, including therapeutic‐dose and …

Initial therapeutic anticoagulation with rivaroxaban compared to prophylactic therapy with heparins in moderate to severe COVID-19: results of the COVID-PREVENT …

U Rauch-Kröhnert, M Puccini, M Placzek… - Clinical Research in …, 2023 - Springer
Background COVID-19 is associated with a prothrombotic state. Current guidelines
recommend prophylactic anticoagulation upon hospitalization. Methods COVID-PREVENT …

Effect of therapeutic versus prophylactic anticoagulation therapy on clinical outcomes in COVID-19 patients: a systematic review with an updated meta-analysis

H Duo, Y Li, Y Sun, L Wei, Z Wang, F Fang, Y Zhong… - Thrombosis …, 2022 - Springer
Background Previous studies demonstrate a reduced risk of thrombosis and mortality with
anticoagulant treatment in patients with COVID-19 than in those without anticoagulation …

Anticoagulation in COVID-19: effect of enoxaparin, heparin, and apixaban on mortality

HH Billett, M Reyes-Gil, J Szymanski… - Thrombosis and …, 2020 - thieme-connect.com
Background Mortality in coronavirus disease of 2019 (COVID-19) is associated with
increases in prothrombotic parameters, particularly D-dimer levels. Anticoagulation has …

The effect of anticoagulation on clinical outcomes in novel Coronavirus (COVID-19) pneumonia in a US cohort

L Lynn, JA Reyes, K Hawkins, A Panda, L Linville… - Thrombosis research, 2021 - Elsevier
Background COVID-19 infection is associated with D-dimer elevations, high rates of
thrombus formation, and poor clinical outcomes. We sought to determine if empiric …