Highlights for dengue immunopathogenesis: antibody-dependent enhancement, cytokine storm, and beyond

D Kuczera, JP Assolini… - Journal of Interferon & …, 2018 - liebertpub.com
Infection with dengue virus (DENV) can lead to a wide spectrum of clinical presentations,
ranging from asymptomatic infection to death. It is estimated that the disease manifests only …

Immune-mediated pathogenesis in dengue virus infection

A Khanam, H Gutiérrez-Barbosa, KE Lyke, JV Chua - Viruses, 2022 - mdpi.com
Dengue virus (DENV) infection is one of the major public health concerns around the globe,
especially in the tropical regions of the world that contribute to 75% percent of dengue …

[HTML][HTML] Inflammatory and innate immune responses in dengue infection: protection versus disease induction

VV Costa, CT Fagundes, DG Souza… - The American journal of …, 2013 - Elsevier
Dengue disease is a mosquito-borne viral disease of expanding geographical range and
incidence. Infection by one of the four serotypes of dengue virus induces a spectrum of …

Mobilization and activation of the innate immune response to dengue virus

CA King, AD Wegman, TP Endy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Dengue virus is an important human pathogen, infecting an estimated 400 million
individuals per year and causing symptomatic disease in a subset of approximately 100 …

Dengue fever: theories of immunopathogenesis and challenges for vaccination

MM Remy - Inflammation & Allergy-Drug Targets (Formerly …, 2014 - ingentaconnect.com
Dengue fever is a mosquito-borne viral disease infecting several hundred million people in
tropical and subtropical areas every year. Its clinical manifestations range from mild fever to …

Dengue infection-recent advances in disease pathogenesis in the era of COVID-19

YK Yong, WF Wong, R Vignesh… - Frontiers in …, 2022 - frontiersin.org
The dynamics of host-virus interactions, and impairment of the host's immune surveillance
by dengue virus (DENV) serotypes largely remain ambiguous. Several experimental and …

Dysfunctional innate immune responses and severe dengue

GN Malavige, C Jeewandara, GS Ogg - Frontiers in cellular and …, 2020 - frontiersin.org
Although infection with the dengue virus (DENV) causes severe dengue, it causes a mild
self-limiting illness in the majority of individuals. There is emerging evidence that an …

Dengue pathogenesis: a disease driven by the host response

BEE Martina - Science progress, 2014 - journals.sagepub.com
Dengue viruses cause mild disease in the majority of infected individuals. In most cases, the
disease is characterised by fever, headache, pain behind the eyes, muscle ache, joint pains …

[HTML][HTML] Antibody response to dengue virus

L Cedillo-Barrón, J García-Cordero… - Microbes and …, 2014 - Elsevier
In this review, we discuss the current knowledge of the role of the antibody response against
dengue virus and highlight novel insights into targets recognized by the human antibody …

Immunopathogenesis versus protection in dengue virus infections

AL Rothman, CL Medin, H Friberg… - Current tropical medicine …, 2014 - Springer
Dengue viruses (DENV) are mosquito-borne viruses that cause significant morbidity. The
existence of four serotypes of DENV with partial immunologic cross-reactivity creates the …