Abstract Interleukin-6 (IL-6) plays a crucial role in host defense against infection and tissue
injuries and is a bioindicator of multiple distinct types of cytokine storms. In this review, we …

The diverse biological activity of interleukin-6 (IL-6) contributes to the maintenance of
homeostasis. Emergent infection or tissue injury induces rapid production of IL-6 and …

Interleukin 6 (IL-6) is a prototypical cytokine for maintaining homeostasis. When
homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and …

Although COVID-19 has become a major challenge to global health, there are currently no
efficacious agents for effective treatment. Cytokine storm syndrome (CSS) can lead to acute …

The elevated circulating levels of cytokines associated with a variety of infectious and
immune-mediated conditions are frequently termed a cytokine storm. Here, we explain the …

Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

IL-6 contributes to host defense against infections and tissue injuries. However,
exaggerated, excessive synthesis of IL-6 while fighting environmental stress leads to an …

Interleukin 6 (IL-6), promptly and transiently produced in response to infections and tissue
injuries, contributes to host defense through the stimulation of acute phase responses …

Abstract Interleukin (IL)-6 is a pleiotropic cytokine that has important roles in the regulation of
the immune response, inflammation, and hematopoiesis. Disruption of IL-6 regulation might …

Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed
threat to people's health and social stability. Mounting evidence suggests that …