Genome-wide association studies have implicated around 250 genomic regions in
predisposition to type 2 diabetes, with evidence for causal variants and genes emerging for …

The global epidemic of type 2 diabetes mellitus (T2D) is one of the most challenging
problems of the 21 st century leading cause of and the fifth death worldwide. Substantial …

Despite numerous candidate gene and linkage studies, the field of type 2 diabetes (T2D)
genetics had until recently succeeded in identifying few genuine disease-susceptibility loci …

To extend understanding of the genetic architecture and molecular basis of type 2 diabetes
(T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including …

The discovery of the association between HLA in the major histocompatibility complex
(MHC) on chromosome 6p21 with type 1 diabetes, but not with type 2 diabetes, suggested …

Type 2 diabetes mellitus has been at the forefront of human diseases and phenotypes
studied by new genetic analyses. Thanks to genome‐wide association studies, we have …

Abstract Purpose of Review Genome-wide association studies have delineated the genetic
architecture of type 2 diabetes. While functional studies to identify target transcripts are …

In recent years, the search for genetic determinants of type 2 diabetes (T2D) has changed
dramatically. Although linkage and small-scale candidate gene studies were highly …

Genome-wide association studies (GWAS) have identified over 70 loci associated with type
2 diabetes (T2D). Most genetic variants associated with T2D are common variants with …

As with other complex diseases, unbiased association studies followed by physiological and
experimental characterization have for years formed a paradigm for identifying genes or …