The scaffold protein IQGAP1 integrates signaling pathways and participates in diverse
cellular activities. IQGAP1 is overexpressed in a number of human solid neoplasms, but its …

IQGAP1 is a key mediator of several distinct cellular processes, in particular cytoskeletal
rearrangements. Recent studies have implicated a potential role for IQGAP1 in cancer …

The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its
expression in hepatocellular carcinoma is unknown. We found that 58% of human …

Simple Summary IQ motif-containing GTPase-activating protein 1 (IQGAP1) is a signal
scaffolding protein that regulates a range of cellular activities by facilitating signal …

The IQGAP family comprises three proteins in humans. The best characterized is IQGAP1,
which participates in protein–protein interactions and integrates diverse signaling pathways …

In eukaryotic cells IQGAP1 binds to and alters the function of several proteins, including
actin, E-cadherin, β-catenin, Cdc42, and Rac1. Yeast IQGAP1 homologues have an …

Background IQGAP1 is a scaffolding protein and overexpressed in many human tumors,
including ovarian cancer. However, the contribution of IQGAP1 to invasive properties of …

Background Pancreatic cancer is a highly aggressive malignant tumor with the lowest
survival rate. A better understanding of the molecular mechanisms which contribute to …

IQGAP1 is a scaffolding protein that can regulate several distinct signaling pathways. The
accumulating evidence has demonstrated that IQGAP1 plays an important role in …

The estrogen receptor (ER) is a steroid hormone receptor that acts as a transcription factor,
modulating genes that regulate a vast range of cellular functions. IQGAP1 interacts with …