Alterations of expression of the serotonin 5-HT4 receptor in brain disorders

H Rebholz, E Friedman, J Castello - International Journal of Molecular …, 2018 - mdpi.com
The serotonin 4 receptor, 5-HT4R, represents one of seven different serotonin receptor
families and is implicated in a variety of physiological functions and their pathophysiological …

Molecular imaging of the 5-HT1A receptor in relation to human cognition

J Borg - Behavioural brain research, 2008 - Elsevier
Animal studies and pharmacological studies in man have suggested that the serotonin 5-
HT1A receptor may serve as a biomarker for cognitive functioning and a target for treatment …

Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction

DE Felsing, NC Anastasio, JM Miszkiel, SR Gilbertson… - PLoS …, 2018 - journals.plos.org
The serotonin (5-HT) 5-HT2A receptor (5-HT2AR) and 5-HT2C receptor (5-HT2CR) in the
central nervous system are implicated in a range of normal behaviors (eg, appetite, sleep) …

The 5-HT6 receptor interactome: New insight in receptor signaling and its impact on brain physiology and pathologies

S Chaumont-Dubel, V Dupuy, J Bockaert, C Bécamel… - …, 2020 - Elsevier
Abstract The serotonin (5-HT) 6 receptor is a Gs-coupled receptor exclusively expressed in
the central nervous system. Highest receptor densities are found in brain regions implicated …

Role of 5-HT3 Receptors in the Antidepressant Response

C Bétry, A Etiévant, C Oosterhof, B Ebert, C Sanchez… - Pharmaceuticals, 2011 - mdpi.com
Serotonin (5-HT) 3 receptors are the only ligand-gated ion channel of the 5-HT receptors
family. They are present both in the peripheral and central nervous system and are localized …

Interplay between Serotonin 5‐HT1A and 5‐HT7 Receptors in Depressive Disorders

VS Naumenko, NK Popova, E Lacivita… - CNS neuroscience & …, 2014 - Wiley Online Library
Summary Serotonin (5‐hydroxytryptamine or 5‐HT) is an important neurotransmitter
regulating a wide range of physiological and pathological functions via activation of …

Htr2a Gene and 5-HT2A Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice

ET Weber, R Andrade - Frontiers in neuroscience, 2010 - frontiersin.org
Serotonin receptors of the 5-HT2A subtype are robustly expressed in the cerebral cortex
where they have been implicated in the pathophysiology and therapeutics of mental …

5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [11C] SB207145 PET in humans

PM Fisher, KK Holst, B Mc Mahon, ME Haahr… - Neuroimage, 2012 - Elsevier
Serotonin (5-HT) is a neuromodulator affecting myriad aspects of personality and behavior
and has been implicated in the pathophysiology of affective disorders including depression …

The 5-HT1A receptor in major depressive disorder

J Kaufman, C DeLorenzo, S Choudhury… - European …, 2016 - Elsevier
Abstract Major Depressive Disorder (MDD) is a highly prevalent psychiatric diagnosis that is
associated with a high degree of morbidity and mortality. This debilitating disorder is …

Serotonin 5‐HT2C receptor protein expression is enriched in synaptosomal and post‐synaptic compartments of rat cortex

NC Anastasio, MF Lanfranco, MJ Bubar… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 113, 1504–1515. Abstract The action of serotonin (5‐HT) at the 5‐
HT2C receptor (5‐HT2CR) in cerebral cortex is emerging as a candidate modulator of …