R Richardson, L Ledgerwood, J Cranney - Learning & Memory, 2004 - learnmem.cshlp.org
Anxiety disorders are among the most common psychological disturbances in the industrialized world. Current behavioral therapy procedures for these disorders are …
The NMDA receptor partial agonist d-cycloserine (DCS) enhances the extinction of learned fear in rats and exposure therapy in humans with anxiety disorders. Despite these benefits …
Administration of benzodiazepines or serotonin reuptake inhibitors in combination with behavior therapy for the treatment of many anxiety disorders has generally lead to only …
SG Hofmann - Depression and anxiety, 2014 - ncbi.nlm.nih.gov
In an attempt to improve the efficacy of psychotherapy for anxiety disorders, preclinical paradigms have recent been translated into novel treatment strategies.[1] Specifically, these …
BACKGROUND: d-cycloserine (DCS) facilitates extinction of learned fear. The aim of this study was to examine whether DCS 1) affects reacquisition of fear (Experiment 1) and 2) …
SG Hofmann, JQ Wu, H Boettcher - Biology of Mood & Anxiety Disorders, 2013 - Springer
The goal of this review is to examine the clinical studies on d-cycloserine, a partial glutamatergic N-methyl-D-aspartate agonist, as an augmentation strategy for exposure …
SG Hofmann - Behaviour research and therapy, 2007 - Elsevier
Combining an effective psychological treatment with conventional anxiolytic medication is typically not more effective than unimodal therapy for treating anxiety disorders. However …
C Grillon - Biological psychiatry, 2009 - Elsevier
Exposure-based therapy, a leading technique in the treatment of a range of anxiety disorders, is facilitated by D-cycloserine (DCS), a partial N-methyl-D-aspartate receptor …
ME Bouton, D Vurbic, AM Woods - Neurobiology of learning and memory, 2008 - Elsevier
d-Cycloserine (DCS) may facilitate fear extinction learning, but the behavioral consequences and mechanisms behind this effect are not well understood at present. In this …