Introduction: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are essential
components of highly active antiretroviral therapy against HIV-1 infections. Here, we provide …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are promising drugs for the
treatment of HIV when used in combination with other anti-HIV drugs such as nucleoside …

Along with nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs),
nonnucleoside reverse transcriptase inhibitors (NNRTIs) have gained a definitive and …

The non-nucleoside reverse transcriptase inhibitors (NNRTIs) are allosteric inhibitors of HIV-
1 reverse transcriptase and are classified into generations depending on their discovery and …

Efavirenz non-nucleoside reverse transcriptase inhibitor (NNRTI)-based therapy or boosted
protease inhibitor (PI)-based therapy are currently recommended as first-line regimens for …

Introduction: There is a continuous need for next-generation non-nucleoside RT inhibitors
(NNRTIs) with different resistance profiles, improved safety, excellent tolerability, and …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have, in addition to the nucleoside
reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), gained a definitive …

It is almost 20 years since NNRTIs were identified as a new class of antiretroviral drugs for
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …

ABSTRACT Introduction: There are 36.7 million people living with HIV with 20.9 million
having access to antiretroviral therapy (ART). Nucleoside/nucleotide reverse transcriptase …

Currently, the long-term usage of non-nucleoside reverse transcriptase inhibitors (NNRTIs)
in HIV/AIDS patients eventually leads to the development of drug resistance and severe side …