[HTML][HTML] Acute lung injury biomarkers in the prediction of COVID-19 severity: Total thiol, ferritin and lactate dehydrogenase

A Martinez Mesa, E Cabrera César, E Martín-Montañez… - Antioxidants, 2021 - mdpi.com
SARS-CoV-2 (COVID-19) patients who develop acute respiratory distress syndrome (ARDS)
can suffer acute lung injury, or even death. Early identification of severe disease is essential …

Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2022 - Elsevier
Abstract oxidative stress is caused by an abundant generation of reactive oxygen species,
associated to a diminished capacity of the endogenous systems of the organism to …

[HTML][HTML] Metabolic implications of oxidative stress and inflammatory process in SARS-CoV-2 pathogenesis: therapeutic potential of natural antioxidants

GE Forcados, A Muhammad, OO Oladipo… - Frontiers in Cellular …, 2021 - frontiersin.org
COVID-19 is a zoonotic disease with devastating economic and public health impacts
globally. Being a novel disease, current research is focused on a clearer understanding of …

[HTML][HTML] Clinical course of COVID-19 patients needing supplemental oxygen outside the intensive care unit

A Daher, P Balfanz, M Aetou, B Hartmann… - Scientific Reports, 2021 - nature.com
Patients suffering from CVOID-19 mostly experience a benign course of the disease.
Approximately 14% of SARS-CoV2 infected patients are admitted to a hospital. Cohorts …

The association between serum levels of micronutrients and the severity of disease in patients with COVID-19

MT Beigmohammadi, S Bitarafan, A Abdollahi… - Nutrition, 2021 - Elsevier
Objectives This study aimed to compare the serum level of micronutrients with normal
amounts, and assess their association with the severity of disease and inflammatory …

SARS-CoV-2 infection pathogenesis is related to oxidative stress as a response to aggression

R Cecchini, AL Cecchini - Medical hypotheses, 2020 - Elsevier
Since the WHO declared COVID-19 a pandemic, a great effort has been made to understand
this serious disease. Thousands of studies are being devoted to understanding its …

Oxidative stress and inflammatory markers in patients with COVID-19: Potential role of RAGE, HMGB1, GFAP and COX-2 in disease severity

FRS Passos, L Heimfarth, BS Monteiro… - International …, 2022 - Elsevier
Background SARS-CoV-2 infection can lead to the abnormal induction of cytokines and a
dysregulated hyperinflammatory state that is implicated in disease severity and risk of death …

[HTML][HTML] Tissue damage from neutrophil-induced oxidative stress in COVID-19

M Laforge, C Elbim, C Frère, M Hémadi… - Nature Reviews …, 2020 - nature.com
The high neutrophil to lymphocyte ratio observed in critically ill patients with COVID-19 is
associated with excessive levels of reactive oxygen species (ROS), which promote a …

[HTML][HTML] The prospective effect of allopurinol on the oxidative stress index and endothelial dysfunction in Covid-19

HM Al-Kuraishy, AI Al-Gareeb, MS Al-Niemi… - Inflammation, 2022 - Springer
SARS-CoV-2 by the direct cytopathic effect or indirectly through the propagation of pro-
inflammatory cytokines could cause endothelial dysfunction (ED) and oxidative stress (OS) …

[HTML][HTML] Hyperglycemia and loss of redox homeostasis in COVID-19 patients

ME Soto, V Guarner-Lans, E Díaz-Díaz… - Cells, 2022 - mdpi.com
The infection with SARS-CoV-2 impairs the glucose–insulin axis and this contributes to
oxidative (OS) and nitrosative (NSS) stress. Here, we evaluated changes in glucose …