Importance Given the high risk of thrombosis and anticoagulation-related bleeding in
patients with hypoxemic COVID-19 pneumonia, identifying the lowest effective dose of …

Early in the courseof the COVID-19 pandemic, thromboembolic complicationswerenotedtofrequentlyoccurin…
with SARS-CoV-2. 1 Infected patients exhibited a unique coagulopathy, referredtoasCOVID …

Background Thrombosis and inflammation may contribute to the risk of death and
complications among patients with coronavirus disease 2019 (Covid-19). We hypothesized …

Background Anticoagulation in hospitalized COVID-19 patients has been associated with
survival benefit; however, the optimal anticoagulant strategy has not yet been defined. The …

Importance Thrombotic events are commonly reported in critically ill patients with COVID-19.
Limited data exist to guide the intensity of antithrombotic prophylaxis. Objective To evaluate …

Background Randomised controlled trials (RCTs) have reported inconsistent effects from
intensified anticoagulation on clinical outcomes in Covid-19. We performed an aggregate …

Background Because of the high risk of thrombotic complications (TCs) during SARS-CoV-2
infection, several scientific societies have proposed to increase the dose of preventive …

Background Thrombotic complications are considered among the main extrapulmonary
manifestations of coronavirus disease 2019 (COVID-19). The optimal type and duration of …

Hypercoagulability in coronavirus disease 2019 (COVID-19) may aggravate disease
severity during hospitalization but the reported survival benefits from anticoagulation (AC) …

Background Optimal thromboprophylaxis for hospitalized patients with coronavirus disease
2019 (Covid-19) is uncertain. Methods In an open-label, adaptive platform trial, we randomly …