Dynamic reconfiguration of brain coactivation states that underlying working memory correlates with cognitive decline in clinically unimpaired older adults

L Li, Z Chen, L Zhang, M Zhang, H Liu, D Wu… - Cerebral …, 2024 - academic.oup.com
Impairments in working memory (WM) are evident in both clinically diagnosed patients with
mild cognitive decline and older adults at risk, as indicated by lower scores on …

Differential spatial working memory–related functional network reconfiguration in young and older adults

WL Yue, KK Ng, S Liu, X Qian, JSX Chong… - Network …, 2024 - direct.mit.edu
Functional brain networks have preserved architectures in rest and task; nevertheless,
previous work consistently demonstrated task-related brain functional reorganization …

Dynamic range of frontoparietal functional modulation is associated with working memory capacity limitations in older adults

JG Hakun, NF Johnson - Brain and cognition, 2017 - Elsevier
Older adults tend to over-activate regions throughout frontoparietal cortices and exhibit a
reduced range of functional modulation during WM task performance compared to younger …

Joint contributions from brain activity and activity‐independent functional connectivity to working memory aging

C Yang, J Fan, K Chen, Z Zhang… - …, 2024 - Wiley Online Library
Working memory (WM) impairment has been well characterized in normal aging. Various
studies have explored changes in either the regional activity or the interregional connectivity …

[HTML][HTML] Age differences in predicting working memory performance from network-based functional connectivity

RN Pläschke, KR Patil, EC Cieslik, AD Nostro… - Cortex, 2020 - Elsevier
Deterioration in working memory capacity (WMC) has been associated with normal aging,
but it remains unknown how age affects the relationship between WMC and connectivity …

A Neural Implementation of Cognitive Reserve: Insights from a Longitudinal fMRI Study of Set-Switching in Aging

F Hasanzadeh, C Habeck, Y Gazes, Y Stern - Neurobiology of Aging, 2024 - Elsevier
Aging is often accompanied by changes in brain structure and executive functions,
particularly in tasks involving cognitive flexibility, such as task-switching. However …

Neocortical-hippocampal dynamics of working memory in healthy and diseased brain states based on functional connectivity

C Poch, P Campo - Frontiers in human neuroscience, 2012 - frontiersin.org
Working memory (WM) is the ability to transiently maintain and manipulate internal
representations beyond its external availability to the senses. This process is thought to …

Age-related changes in neural activity during performance matched working memory manipulation

L Emery, TJ Heaven, JL Paxton, TS Braver - Neuroimage, 2008 - Elsevier
A long-standing assumption in the cognitive aging literature is that performance on working
memory (WM) tasks involving serial recall is relatively unaffected by aging, whereas tasks …

Linking cognitive integrity to working memory dynamics in the aging human brain

G Monov, H Stein, L Klock, J Gallinat… - Journal of …, 2024 - Soc Neuroscience
Aging is accompanied by a decline of working memory, an important cognitive capacity that
involves stimulus-selective neural activity that persists after stimulus presentation. Here, we …

Behavioral and neural markers of flexible attention over working memory in aging

RM Mok, NE Myers, G Wallis, AC Nobre - Cerebral Cortex, 2016 - academic.oup.com
Working memory (WM) declines as we age and, because of its fundamental role in higher
order cognition, this can have highly deleterious effects in daily life. We investigated whether …