[HTML][HTML] Elevated interleukin-10 levels in COVID-19: potentiation of pro-inflammatory responses or impaired anti-inflammatory action?

H Islam, TC Chamberlain, AL Mui, JP Little - Frontiers in Immunology, 2021 - frontiersin.org
Interleukin (IL)-10 is a pleiotropic cytokine known for its potent anti-inflammatory and
immunosuppressive effects. Originally identified as a product of T helper 2 cells, IL-10 is now …

[HTML][HTML] A potential role of interleukin 10 in COVID-19 pathogenesis

L Lu, H Zhang, DJ Dauphars, YW He - Trends in Immunology, 2021 - cell.com
A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the
dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback …

[HTML][HTML] The anti-inflammatory cytokine response characterized by elevated interleukin-10 is a stronger predictor of severe disease and poor outcomes than the pro …

BM Henry, SW Benoit, J Vikse, BA Berger… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives Severe coronavirus disease 2019 (COVID-19) is associated with a dysregulated
immune state. While research has focused on the hyperinflammation, little research has …

The role of IL-6 and IL-6 blockade in COVID-19

N Potere, A Batticciotto, A Vecchié… - Expert review of …, 2021 - Taylor & Francis
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …

May IL-17 have a role in COVID-19 infection?

M Megna, M Napolitano, G Fabbrocini - Medical hypotheses, 2020 - ncbi.nlm.nih.gov
SARS-Corona-Virus-2 related disease (COVID-19) which started in Wuhan, China on
December 2019, is spreading rapidly throughout the world [1]. COVID-19 clinical spectrum is …

The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics

M Abbasifard, H Khorramdelazad - Life sciences, 2020 - Elsevier
Abstract Interleukin-6 (IL-6), known as an inflammatory cytokine, can be involved in many
innate and adaptive immune responses. The role of IL-6 in the pathogenesis of the novel …

[HTML][HTML] The role of IL-6 in coronavirus, especially in COVID-19

X Wang, G Tang, Y Liu, L Zhang, B Chen… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects both people and
animals and may cause significant respiratory problems, including lung illness: Corona …

Interleukin‐6 in COVID‐19: a systematic review and meta‐analysis

EA Coomes, H Haghbayan - Reviews in medical virology, 2020 - Wiley Online Library
Coronaviruses may activate dysregulated host immune responses. As exploratory studies
have suggested that interleukin‐6 (IL‐6) levels are elevated in cases of complicated Covid …

Interleukin-1 in COVID-19 Infection: Immunopathogenesis and Possible Therapeutic Perspective

A Mardi, S Meidaninikjeh, S Nikfarjam… - Viral …, 2021 - liebertpub.com
The newfound coronavirus disease 2019 (COVID-19), initiated by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is an international public health concern …

Relationship between IL-6 and COVID-19: to be considered during treatment

HS Vatansever, E Becer - Future Virology, 2020 - Future Medicine
The detection and control of pro-inflammatory response is crucial in the early stages of viral
infection. Coronavirus disease 2019 (COVID-19) is an emerging viral disease of global …