The CCR5 is a chemokine receptor widely expressed by several immune cells that are
engaged in inflammatory responses. Some populations have individuals exhibiting a 32 bp …

Chemokines are low-molecular weight proteins that play a key role in inflammatory
processes. Genomic variations in chemokine receptors are associated with the susceptibility …

The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

Although a potential involvement of the CCR5Δ32 variant has already been suggested in
relation to susceptibility to hepatitis C virus (HCV) infection, data from the literature is still …

Background Chemokine receptors CCR2 and CCR5 play a key role in immune and
inflammatory responses and have been associated with several diseases, including AIDS. In …

Recent evidence has demonstrated the role of CCR5Δ32 in a variety of human diseases:
from infectious and inflammatory diseases to cancer. Several studies have confirmed that …

Background The human immunodeficiency virus type 1 (HIV-1) infection occurs by binding
to CD4+ receptor and chemokine receptor 5 (CCR5) or the CXC chemokine receptor …

The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The
effect of the CCR5* D32 allele in susceptibility to HIV infection and AIDS disease is well …

Background: Ligands of chemokine receptor CCR5, including MIP-1α, MIP-1β, and
RANTES, have been implicated in rheumatoid arthritis. Objective: To test whether CCR5 d32 …

The frequency of CCR5-Δ32 allele in human immunodeficiency virus type 1 (HIV-1) infection
in the southern Brazilian population was determined in a cross-sectional study carried out …