Construction and validation of a novel immunosignature for overall survival in uveal melanoma

C Gu, X Gu, Y Wang, Z Yao, C Zhou - Frontiers in Cell and …, 2021 - frontiersin.org
Objectives Uveal melanoma (UM) is the most common primary intraocular malignancy in
adults, and immune infiltration plays a crucial role in the prognosis of UM. This study aimed …

Identification of a prognostic six-immune-gene signature and a nomogram model for uveal melanoma

B Yang, Y Fan, R Liang, Y Wu, A Gu - BMC ophthalmology, 2023 - Springer
Background To identify an immune-related prognostic signature and find potential
therapeutic targets for uveal melanoma. Methods The RNA-sequencing data obtained from …

[HTML][HTML] Identification of an immune-related signature for the prognosis of uveal melanoma

YZ Li, Y Huang, XY Deng, CS Tu - International Journal of …, 2020 - ncbi.nlm.nih.gov
AIM To construct an immune-related prognostic signature (IPS) that can distinguish and
predict prognosis in uveal melanoma (UM). METHODS The transcriptomic data and …

Identification and validation of an immune-relevant risk signature predicting survival outcome and immune infiltration in uveal melanoma

X Sun, Q Li, G Xu - International Ophthalmology, 2023 - Springer
Purpose The current study aimed to reveal a novel immune-related signature to evaluate
immune infiltration status and the survival outcome for patients with uveal melanoma (UM) …

Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk …

W Wang, H Zhao, S Wang - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Uveal melanoma (UVM) is the most invasive intraocular malignancy in adults
with a poor prognosis. Growing evidence revealed that immune-related gene is related to …

Immunogenic profiling of metastatic uveal melanoma discerns a potential signature related to prognosis

J Wang, M Liu, J Sun, Z Zhang - Journal of Cancer Research and Clinical …, 2024 - Springer
Background Uveal melanoma (UM) is an aggressive intraocular malignant tumor. The
present study aimed to identify the key genes associated with UM metastasis and …

Immune classification and identification of prognostic genes for uveal melanoma based on six immune cell signatures

G Gao, Z Yu, X Zhao, X Fu, S Liu, S Liang, A Deng - Scientific Reports, 2021 - nature.com
Cutaneous melanoma could be treated by immunotherapy, which only has limited efficacy
on uveal melanoma (UM). UM immunotyping for predicting immunotherapeutic responses …

Development and validation of immunogenic cell death-related signature for predicting the prognosis and immune landscape of uveal melanoma

Y Hu, J Cai, M Ye, Q Mou, B Zhao, Q Sun… - Frontiers in …, 2022 - frontiersin.org
Introduction Uveal melanoma (UM) is the most common primary intraocular malignant tumor
in adults, and the main treatment for UM is currently surgery and plaque brachytherapy. UM …

Identification of immune cell infiltration landscape and their prognostic significance in uveal melanoma

H Zhao, Y Chen, P Shen, L Gong - Frontiers in Cell and …, 2021 - frontiersin.org
Uveal melanoma (UVM) is the most common primary intraocular cancer in adults. Increasing
evidence has demonstrated that immune cell infiltration (ICI) is crucial in predicting patient …

Integrated single-cell and transcriptome sequencing analyses develops a metastasis-based risk score system for prognosis and immunotherapy response in uveal …

S Meng, T Zhu, Z Fan, Y Cheng, Y Dong… - Frontiers in …, 2023 - frontiersin.org
Background: Uveal melanoma (UM) is the most frequent ocular neoplasm with a strong
metastatic ability. The prognostic value of metastasis-associated genes (MAGs) of UM …